6-Methyl­sulfanyl-4H-pyrimido[1,6-a]pyrimidin-4-one

Reaction of 2-(methyl­sulfan­yl)pyrimidin-4-amine with the 5-(methoxy­vinyl­idene) derivative of Meldrum’s acid and subsequent heating of the product in Dowtherm fluid yielded the title compound, C(8)H(7)N(3)OS, which was proven to contain a bicyclic 4H-pyrimido[1,6-a]pyrimidine system. All non-H at...

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Detalles Bibliográficos
Autores principales: Huang, Quinhua, Richardson, Paul F., Rui, Eugene, Rheingold, Arnold L., Yanovsky, Alex
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970259/
https://www.ncbi.nlm.nih.gov/pubmed/21578009
http://dx.doi.org/10.1107/S1600536809038562
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author Huang, Quinhua
Richardson, Paul F.
Rui, Eugene
Rheingold, Arnold L.
Yanovsky, Alex
author_facet Huang, Quinhua
Richardson, Paul F.
Rui, Eugene
Rheingold, Arnold L.
Yanovsky, Alex
author_sort Huang, Quinhua
collection PubMed
description Reaction of 2-(methyl­sulfan­yl)pyrimidin-4-amine with the 5-(methoxy­vinyl­idene) derivative of Meldrum’s acid and subsequent heating of the product in Dowtherm fluid yielded the title compound, C(8)H(7)N(3)OS, which was proven to contain a bicyclic 4H-pyrimido[1,6-a]pyrimidine system. All non-H atoms of the mol­ecule are coplanar within 0.15 Å. The bond-length distribution in the bicyclic core shows localization of the double bonds. The geometry of the intra­molecular S⋯O 1,5-contact [2.534 (2) Å] is consistent with the existence of an attractive inter­action.
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spelling pubmed-29702592010-12-30 6-Methyl­sulfanyl-4H-pyrimido[1,6-a]pyrimidin-4-one Huang, Quinhua Richardson, Paul F. Rui, Eugene Rheingold, Arnold L. Yanovsky, Alex Acta Crystallogr Sect E Struct Rep Online Organic Papers Reaction of 2-(methyl­sulfan­yl)pyrimidin-4-amine with the 5-(methoxy­vinyl­idene) derivative of Meldrum’s acid and subsequent heating of the product in Dowtherm fluid yielded the title compound, C(8)H(7)N(3)OS, which was proven to contain a bicyclic 4H-pyrimido[1,6-a]pyrimidine system. All non-H atoms of the mol­ecule are coplanar within 0.15 Å. The bond-length distribution in the bicyclic core shows localization of the double bonds. The geometry of the intra­molecular S⋯O 1,5-contact [2.534 (2) Å] is consistent with the existence of an attractive inter­action. International Union of Crystallography 2009-09-30 /pmc/articles/PMC2970259/ /pubmed/21578009 http://dx.doi.org/10.1107/S1600536809038562 Text en © Huang et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Huang, Quinhua
Richardson, Paul F.
Rui, Eugene
Rheingold, Arnold L.
Yanovsky, Alex
6-Methyl­sulfanyl-4H-pyrimido[1,6-a]pyrimidin-4-one
title 6-Methyl­sulfanyl-4H-pyrimido[1,6-a]pyrimidin-4-one
title_full 6-Methyl­sulfanyl-4H-pyrimido[1,6-a]pyrimidin-4-one
title_fullStr 6-Methyl­sulfanyl-4H-pyrimido[1,6-a]pyrimidin-4-one
title_full_unstemmed 6-Methyl­sulfanyl-4H-pyrimido[1,6-a]pyrimidin-4-one
title_short 6-Methyl­sulfanyl-4H-pyrimido[1,6-a]pyrimidin-4-one
title_sort 6-methyl­sulfanyl-4h-pyrimido[1,6-a]pyrimidin-4-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970259/
https://www.ncbi.nlm.nih.gov/pubmed/21578009
http://dx.doi.org/10.1107/S1600536809038562
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AT rheingoldarnoldl 6methylsulfanyl4hpyrimido16apyrimidin4one
AT yanovskyalex 6methylsulfanyl4hpyrimido16apyrimidin4one

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