2-(3-Ethyl­sulfanyl-5-fluoro-1-benzofuran-2-yl)acetic acid

The title compound, C(12)H(11)FO(3)S, was prepared by alkaline hydrolysis of ethyl 2–(3–ethyl­sulfan­yl–5–fluoro–1–benzofuran–2–­yl) acetate. In the crystal structure, the carboxyl groups are involved in inter­molecular O—H⋯O hydrogen bonds, which link the mol­ecules into centrosymmetric dimers. The...

Descripción completa

Detalles Bibliográficos
Autores principales: Choi, Hong Dae, Seo, Pil Ja, Son, Byeng Wha, Lee, Uk
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970325/
https://www.ncbi.nlm.nih.gov/pubmed/21577933
http://dx.doi.org/10.1107/S160053680903671X
_version_ 1782190412822216704
author Choi, Hong Dae
Seo, Pil Ja
Son, Byeng Wha
Lee, Uk
author_facet Choi, Hong Dae
Seo, Pil Ja
Son, Byeng Wha
Lee, Uk
author_sort Choi, Hong Dae
collection PubMed
description The title compound, C(12)H(11)FO(3)S, was prepared by alkaline hydrolysis of ethyl 2–(3–ethyl­sulfan­yl–5–fluoro–1–benzofuran–2–­yl) acetate. In the crystal structure, the carboxyl groups are involved in inter­molecular O—H⋯O hydrogen bonds, which link the mol­ecules into centrosymmetric dimers. These dimers are further packed into stacks along the b axis by aromatic π–π inter­actions between the furan ring and the benzene ring of neighbouring benzofuran ring systems [centroid–centroid distance = 3.684 (5) Å].
format Text
id pubmed-2970325
institution National Center for Biotechnology Information
language English
publishDate 2009
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-29703252010-12-30 2-(3-Ethyl­sulfanyl-5-fluoro-1-benzofuran-2-yl)acetic acid Choi, Hong Dae Seo, Pil Ja Son, Byeng Wha Lee, Uk Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(12)H(11)FO(3)S, was prepared by alkaline hydrolysis of ethyl 2–(3–ethyl­sulfan­yl–5–fluoro–1–benzofuran–2–­yl) acetate. In the crystal structure, the carboxyl groups are involved in inter­molecular O—H⋯O hydrogen bonds, which link the mol­ecules into centrosymmetric dimers. These dimers are further packed into stacks along the b axis by aromatic π–π inter­actions between the furan ring and the benzene ring of neighbouring benzofuran ring systems [centroid–centroid distance = 3.684 (5) Å]. International Union of Crystallography 2009-09-16 /pmc/articles/PMC2970325/ /pubmed/21577933 http://dx.doi.org/10.1107/S160053680903671X Text en © Choi et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Choi, Hong Dae
Seo, Pil Ja
Son, Byeng Wha
Lee, Uk
2-(3-Ethyl­sulfanyl-5-fluoro-1-benzofuran-2-yl)acetic acid
title 2-(3-Ethyl­sulfanyl-5-fluoro-1-benzofuran-2-yl)acetic acid
title_full 2-(3-Ethyl­sulfanyl-5-fluoro-1-benzofuran-2-yl)acetic acid
title_fullStr 2-(3-Ethyl­sulfanyl-5-fluoro-1-benzofuran-2-yl)acetic acid
title_full_unstemmed 2-(3-Ethyl­sulfanyl-5-fluoro-1-benzofuran-2-yl)acetic acid
title_short 2-(3-Ethyl­sulfanyl-5-fluoro-1-benzofuran-2-yl)acetic acid
title_sort 2-(3-ethyl­sulfanyl-5-fluoro-1-benzofuran-2-yl)acetic acid
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970325/
https://www.ncbi.nlm.nih.gov/pubmed/21577933
http://dx.doi.org/10.1107/S160053680903671X
work_keys_str_mv AT choihongdae 23ethylsulfanyl5fluoro1benzofuran2ylaceticacid
AT seopilja 23ethylsulfanyl5fluoro1benzofuran2ylaceticacid
AT sonbyengwha 23ethylsulfanyl5fluoro1benzofuran2ylaceticacid
AT leeuk 23ethylsulfanyl5fluoro1benzofuran2ylaceticacid

Ejemplares similares