Cargando…

Profiling Gene Expression Induced by Protease-Activated Receptor 2 (PAR2) Activation in Human Kidney Cells

Protease-Activated Receptor-2 (PAR2) has been implicated through genetic knockout mice with cytokine regulation and arthritis development. Many studies have associated PAR2 with inflammatory conditions (arthritis, airways inflammation, IBD) and key events in tumor progression (angiogenesis, metastas...

Descripción completa

Detalles Bibliográficos
Autores principales:	Suen, Jacky Y., Gardiner, Brooke, Grimmond, Sean, Fairlie, David P.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970545/ https://www.ncbi.nlm.nih.gov/pubmed/21072196 http://dx.doi.org/10.1371/journal.pone.0013809

Ejemplares similares

Expression of protease activated receptor-2 is reduced in renal cell carcinoma biopsies and cell lines
por: Morais, Christudas, et al.
Publicado: (2021)

Protease-activated receptor (PAR)-2 is required for PAR-1 signalling in pulmonary fibrosis
por: Lin, Cong, et al.
Publicado: (2015)

Histone 2B Facilitates Plasminogen-Enhanced Endothelial Migration through Protease-Activated Receptor 1 (PAR1) and Protease-Activated Receptor 2 (PAR2)
por: Das, Mitali, et al.
Publicado: (2022)

Humanizing the Protease-Activated Receptor (PAR) Expression Profile in Mouse Platelets by Knocking PAR1 into the Par3 Locus Reveals PAR1 Expression Is Not Tolerated in Mouse Platelets
por: French, Shauna L., et al.
Publicado: (2016)

Predictive value of protease‐activated receptor‐2 (PAR(2)) in cervical cancer metastasis
por: He, Shengnan, et al.
Publicado: (2020)

Attenuated Vasodilator Effectiveness of Protease-Activated Receptor 2 Agonist in Heterozygous par2 Knockout Mice
por: Hennessey, John C., et al.
Publicado: (2013)

Targeting of protease activator receptor-2 (PAR-2) antagonist FSLLRY-NH2 as an asthma adjuvant therapy
por: Ocasio-Rivera, Marinel, et al.
Publicado: (2020)

Protease-activated receptors (PARs)—biology and role in cancer invasion and metastasis
por: Wojtukiewicz, Marek Z., et al.
Publicado: (2015)

Chemical Tools to Image the Activity of PAR-Cleaving Proteases
por: Lee, Irene Y., et al.
Publicado: (2023)

Protease-activated receptors (PARs): mechanisms of action and potential therapeutic modulators in PAR-driven inflammatory diseases
por: Heuberger, Dorothea M., et al.
Publicado: (2019)

Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis
por: Huang, Xiaojian, et al.
Publicado: (2019)

Expression of protease activating receptor-2 (PAR-2) is positively correlated with the recurrence of non-muscle invasive bladder cancer: an immunohistochemical analysis
por: Nakahara, Kozue, et al.
Publicado: (2019)

A protease activated receptor-2 (PAR-2) activating peptide, tc-LIGRLO-NH(2), induces protease release from mast cells: role in TNF degradation
por: Alshurafa, Hashem N, et al.
Publicado: (2004)

Correction to: protease-activated receptors (PARs): mechanisms of action and potential therapeutic modulators in PAR-driven inflammatory diseases
por: Heuberger, Dorothea M., et al.
Publicado: (2019)

Emerging Roles of Protease-Activated Receptors (PARs) in the Modulation of Synaptic Transmission and Plasticity
por: Price, Rachel, et al.
Publicado: (2021)

Increased Protease-Activated Receptor-2 (PAR-2) Expression on CD14(++)CD16(+) Peripheral Blood Monocytes of Patients with Severe Asthma
por: Shrestha Palikhe, Nami, et al.
Publicado: (2015)

Development and Evaluation of Small Peptidomimetic Ligands to Protease-Activated Receptor-2 (PAR(2)) through the Use of Lipid Tethering
por: Boitano, Scott, et al.
Publicado: (2014)

Complement factor C4a does not activate protease‐activated receptor 1 (PAR1) or PAR4 on human platelets
por: Han, Xu, et al.
Publicado: (2020)

Activation of protease-activated receptors (PARs)-1 and -2 promotes alpha-smooth muscle actin expression and release of cytokines from human lung fibroblasts
por: Asokananthan, Nithiananthan, et al.
Publicado: (2015)

Protease-activated receptor-2 ligands reveal orthosteric and allosteric mechanisms of receptor inhibition
por: Kennedy, Amanda J., et al.
Publicado: (2020)

Candida albicans Sap6 Initiates Oral Mucosal Inflammation via the Protease Activated Receptor PAR2
por: Kumar, Rohitashw, et al.
Publicado: (2022)

Protease-activated receptor-1 (PAR-1): a promising molecular target for cancer
por: Liu, Xuan, et al.
Publicado: (2017)

Protease-Activated Receptor 4 (PAR4): A Promising Target for Antiplatelet Therapy
por: Rwibasira Rudinga, Gamariel, et al.
Publicado: (2018)

Role of protease‐activated receptor‐1 (PAR‐1) in the glomerular filtration barrier integrity
por: Medipally, Ajay, et al.
Publicado: (2022)

Platelet Specific Promoters Are Insufficient to Express Protease Activated Receptor 1 (PAR1) Transgene in Mouse Platelets
por: Arachiche, Amal, et al.
Publicado: (2014)

Intrinsic Expression of Coagulation Factors and Protease Activated Receptor 1 (PAR1) in Photoreceptors and Inner Retinal Layers
por: Goldberg, Zehavit, et al.
Publicado: (2022)

Novel Role for Proteinase-activated Receptor 2 (PAR(2)) in Membrane Trafficking of Proteinase-activated Receptor 4 (PAR(4))
por: Cunningham, Margaret R., et al.
Publicado: (2012)

C781, a β-Arrestin Biased Antagonist at Protease-Activated Receptor-2 (PAR2), Displays in vivo Efficacy Against Protease-Induced Pain in Mice
por: Kume, Moeno, et al.
Publicado: (2023)

Antagonism of the proinflammatory and pronociceptive actions of canonical and biased agonists of protease‐activated receptor‐2
por: Lieu, T, et al.
Publicado: (2016)

Protease-Activated Receptor (PAR)2, but Not PAR1, Is Involved in Collateral Formation and Anti-Inflammatory Monocyte Polarization in a Mouse Hind Limb Ischemia Model
por: van den Hengel, Lisa G., et al.
Publicado: (2013)

Proteinase-activated receptor-2 (PAR-2) expression on inflammatory cells in severe asthma
por: Nahirney, Drew, et al.
Publicado: (2014)

Calcium Mobilization And Protein Kinase C Activation Downstream Of Protease Activated Receptor 4 (PAR4) Is Negatively Regulated By PAR3 In Mouse Platelets
por: Arachiche, Amal, et al.
Publicado: (2013)

Protease Activated Receptor 2 (PAR2) Induces Long-Term Depression in the Hippocampus through Transient Receptor Potential Vanilloid 4 (TRPV4)
por: Shavit-Stein, Efrat, et al.
Publicado: (2017)

Potential importance of protease activated receptor (PAR)-1 expression in the tumor stroma of non-small-cell lung cancer
por: Lin, Cong, et al.
Publicado: (2017)

PAR2 Activation on Human Kidney Tubular Epithelial Cells Induces Tissue Factor Synthesis, That Enhances Blood Clotting
por: Iyer, Abishek, et al.
Publicado: (2021)

Transcription factor network downstream of protease activated receptors (PARs) modulating mouse bladder inflammation
por: Saban, Ricardo, et al.
Publicado: (2007)

Developmental Role of Zebrafish Protease-Activated Receptor 1 (PAR1) in the Cardio-Vascular System
por: Ellertsdottir, Elin, et al.
Publicado: (2012)

Antithrombotic Effects of Combined PAR (Protease-Activated Receptor)-4 Antagonism and Factor Xa Inhibition
por: Meah, Mohammed N., et al.
Publicado: (2020)

A6 PROTEASE-ACTIVATED RECEPTOR (PAR)-2 ACTIVATION ENHANCES EPITHELIAL WOUND HEALING MIGRATION THROUGH SRC AND RAC1 PATHWAYS
por: Lucena Perico, L, et al.
Publicado: (2023)

Blood pressures, heart rate and locomotor activity during salt loading and angiotensin II infusion in protease-activated receptor 2 (PAR(2)) knockout mice
por: McGuire, John J, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_2d52522c5bmjd5vd0a7g6g51rb