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Clinical implications of novel activating EGFR mutations in malignant peritoneal mesothelioma

BACKGROUND: There is a paucity of information about the molecular perturbations involved in MPM tumor formation. We previously reported that EGFR-TK mutations in MPM were predictive of achieving optimal surgical cytoreduction, but the status of EGFR pathway activation potential of these mutations wa...

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Detalles Bibliográficos
Autores principales: Foster, Jason M, Radhakrishna, Uppala, Govindarajan, Venkatesh, Carreau, Joseph H, Gatalica, Zoran, Sharma, Poonam, Nath, Swapan K, Loggie, Brian W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970593/
https://www.ncbi.nlm.nih.gov/pubmed/20942962
http://dx.doi.org/10.1186/1477-7819-8-88

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