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Human functional genetic studies are biased against the medically most relevant primate-specific genes
BACKGROUND: Many functional, structural and evolutionary features of human genes have been observed to correlate with expression breadth and/or gene age. Here, we systematically explore these correlations. RESULTS: Gene age and expression breadth are strongly correlated, but contribute independently...
Autores principales: | Hao, Lili, Ge, Xiaomeng, Wan, Haolei, Hu, Songnian, Lercher, Martin J, Yu, Jun, Chen, Wei-Hua |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970608/ https://www.ncbi.nlm.nih.gov/pubmed/20961448 http://dx.doi.org/10.1186/1471-2148-10-316 |
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