2-Morpholino-4-oxo-4,5-dihydro­thio­phene-3-carbonitrile

The title compound, C(9)H(10)N(2)O(2)S, was obtained from the treatment of ethyl 4-cyano-3-hydr­oxy-5-morpholinothio­phene-2-carboxyl­ate with concentrated HCl. The mean plane of the essentially planar dihydro­thio­phene ring is almost orthogonal to the mirror plane of the N-morpholine substituent,...

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Detalles Bibliográficos
Autores principales: Zhu, JinJiang, Liu, Kevin K., Marx, Matthew A., Rheingold, Arnold L., Yanovsky, Alex
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970977/
https://www.ncbi.nlm.nih.gov/pubmed/21578359
http://dx.doi.org/10.1107/S1600536809041737
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author Zhu, JinJiang
Liu, Kevin K.
Marx, Matthew A.
Rheingold, Arnold L.
Yanovsky, Alex
author_facet Zhu, JinJiang
Liu, Kevin K.
Marx, Matthew A.
Rheingold, Arnold L.
Yanovsky, Alex
author_sort Zhu, JinJiang
collection PubMed
description The title compound, C(9)H(10)N(2)O(2)S, was obtained from the treatment of ethyl 4-cyano-3-hydr­oxy-5-morpholinothio­phene-2-carboxyl­ate with concentrated HCl. The mean plane of the essentially planar dihydro­thio­phene ring is almost orthogonal to the mirror plane of the N-morpholine substituent, making a dihedral angle of 87.2 (2)°.
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spelling pubmed-29709772010-12-30 2-Morpholino-4-oxo-4,5-dihydro­thio­phene-3-carbonitrile Zhu, JinJiang Liu, Kevin K. Marx, Matthew A. Rheingold, Arnold L. Yanovsky, Alex Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(9)H(10)N(2)O(2)S, was obtained from the treatment of ethyl 4-cyano-3-hydr­oxy-5-morpholinothio­phene-2-carboxyl­ate with concentrated HCl. The mean plane of the essentially planar dihydro­thio­phene ring is almost orthogonal to the mirror plane of the N-morpholine substituent, making a dihedral angle of 87.2 (2)°. International Union of Crystallography 2009-10-17 /pmc/articles/PMC2970977/ /pubmed/21578359 http://dx.doi.org/10.1107/S1600536809041737 Text en © Zhu et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Zhu, JinJiang
Liu, Kevin K.
Marx, Matthew A.
Rheingold, Arnold L.
Yanovsky, Alex
2-Morpholino-4-oxo-4,5-dihydro­thio­phene-3-carbonitrile
title 2-Morpholino-4-oxo-4,5-dihydro­thio­phene-3-carbonitrile
title_full 2-Morpholino-4-oxo-4,5-dihydro­thio­phene-3-carbonitrile
title_fullStr 2-Morpholino-4-oxo-4,5-dihydro­thio­phene-3-carbonitrile
title_full_unstemmed 2-Morpholino-4-oxo-4,5-dihydro­thio­phene-3-carbonitrile
title_short 2-Morpholino-4-oxo-4,5-dihydro­thio­phene-3-carbonitrile
title_sort 2-morpholino-4-oxo-4,5-dihydro­thio­phene-3-carbonitrile
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970977/
https://www.ncbi.nlm.nih.gov/pubmed/21578359
http://dx.doi.org/10.1107/S1600536809041737
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AT marxmatthewa 2morpholino4oxo45dihydrothiophene3carbonitrile
AT rheingoldarnoldl 2morpholino4oxo45dihydrothiophene3carbonitrile
AT yanovskyalex 2morpholino4oxo45dihydrothiophene3carbonitrile

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