3-(4-Fluoro­phen­yl)-2-(2-naphth­yloxy)-4-oxo-5-phenyl-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidine-7-carbonitrile

The title compound, C(29)H(17)FN(4)O(2), may be used as a new precursor for obtaining bioactive mol­ecules. There are two crystallographically independent mol­ecules in the asymmetric unit. The phenyl ring, 4-fluoro­phenyl ring and 2-naphth­yloxy ring are twisted with respect to the pyrrolopyrimidin...

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Detalles Bibliográficos
Autores principales: Ma, Jun-Kai, He, Mei, Hu, Yang-Gen
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970989/
https://www.ncbi.nlm.nih.gov/pubmed/21578245
http://dx.doi.org/10.1107/S1600536809039531
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author Ma, Jun-Kai
He, Mei
Hu, Yang-Gen
author_facet Ma, Jun-Kai
He, Mei
Hu, Yang-Gen
author_sort Ma, Jun-Kai
collection PubMed
description The title compound, C(29)H(17)FN(4)O(2), may be used as a new precursor for obtaining bioactive mol­ecules. There are two crystallographically independent mol­ecules in the asymmetric unit. The phenyl ring, 4-fluoro­phenyl ring and 2-naphth­yloxy ring are twisted with respect to the pyrrolopyrimidine ring by 52.30 (11)/49.05 (11), 80.94 (10)/88.36 (10) and 60.58 (7)/83.76 (7)°, respectively. The crystal packing is stabilized by weak C—H⋯N hydrogen bonds.
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spelling pubmed-29709892010-12-30 3-(4-Fluoro­phen­yl)-2-(2-naphth­yloxy)-4-oxo-5-phenyl-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidine-7-carbonitrile Ma, Jun-Kai He, Mei Hu, Yang-Gen Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(29)H(17)FN(4)O(2), may be used as a new precursor for obtaining bioactive mol­ecules. There are two crystallographically independent mol­ecules in the asymmetric unit. The phenyl ring, 4-fluoro­phenyl ring and 2-naphth­yloxy ring are twisted with respect to the pyrrolopyrimidine ring by 52.30 (11)/49.05 (11), 80.94 (10)/88.36 (10) and 60.58 (7)/83.76 (7)°, respectively. The crystal packing is stabilized by weak C—H⋯N hydrogen bonds. International Union of Crystallography 2009-10-03 /pmc/articles/PMC2970989/ /pubmed/21578245 http://dx.doi.org/10.1107/S1600536809039531 Text en © Ma et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Ma, Jun-Kai
He, Mei
Hu, Yang-Gen
3-(4-Fluoro­phen­yl)-2-(2-naphth­yloxy)-4-oxo-5-phenyl-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidine-7-carbonitrile
title 3-(4-Fluoro­phen­yl)-2-(2-naphth­yloxy)-4-oxo-5-phenyl-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidine-7-carbonitrile
title_full 3-(4-Fluoro­phen­yl)-2-(2-naphth­yloxy)-4-oxo-5-phenyl-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidine-7-carbonitrile
title_fullStr 3-(4-Fluoro­phen­yl)-2-(2-naphth­yloxy)-4-oxo-5-phenyl-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidine-7-carbonitrile
title_full_unstemmed 3-(4-Fluoro­phen­yl)-2-(2-naphth­yloxy)-4-oxo-5-phenyl-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidine-7-carbonitrile
title_short 3-(4-Fluoro­phen­yl)-2-(2-naphth­yloxy)-4-oxo-5-phenyl-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidine-7-carbonitrile
title_sort 3-(4-fluoro­phen­yl)-2-(2-naphth­yloxy)-4-oxo-5-phenyl-4,5-dihydro-3h-pyrrolo[3,2-d]pyrimidine-7-carbonitrile
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970989/
https://www.ncbi.nlm.nih.gov/pubmed/21578245
http://dx.doi.org/10.1107/S1600536809039531
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AT huyanggen 34fluorophenyl22naphthyloxy4oxo5phenyl45dihydro3hpyrrolo32dpyrimidine7carbonitrile

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