Cargando…
3-Benzyl-7-methoxy-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexahydro-1H-pyrrolo[3,4-b]quinoline
In the title compound, C(32)H(32)N(2)O(3)S, the pyrrolidine ring adopts an envelope conformation with the methine C atom nearest to the phenyl ring as the flap atom. The tetrahydropyridine ring has a half-chair conformation. The two rings are trans-fused. The phenyl ring bound to the tetrahydrop...
Autores principales: | , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971011/ https://www.ncbi.nlm.nih.gov/pubmed/21578528 http://dx.doi.org/10.1107/S1600536809044973 |
_version_ | 1782190524990488576 |
---|---|
author | Chinnakali, K. Sudha, D. Jayagobi, M. Raghunathan, R. Fun, Hoong-Kun |
author_facet | Chinnakali, K. Sudha, D. Jayagobi, M. Raghunathan, R. Fun, Hoong-Kun |
author_sort | Chinnakali, K. |
collection | PubMed |
description | In the title compound, C(32)H(32)N(2)O(3)S, the pyrrolidine ring adopts an envelope conformation with the methine C atom nearest to the phenyl ring as the flap atom. The tetrahydropyridine ring has a half-chair conformation. The two rings are trans-fused. The phenyl ring bound to the tetrahydropyridine is oriented almost perpendicular [dihedral angle = 86.35 (10)°] to the fused benzene ring. The dihedral angle between the benzylphenyl ring and the sulfonyl-bound phenyl ring is 69.43 (10)°. A very weak N—H⋯π interaction is observed in the molecular structure. In the crystal, molecules translated one unit along the b axis are linked into C(10) chains by C—H⋯O hydrogen bonds; adjacent chains are linked via C—H⋯π interactions, forming a two-dimensional network parallel to the bc plane. |
format | Text |
id | pubmed-2971011 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-29710112010-12-30 3-Benzyl-7-methoxy-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexahydro-1H-pyrrolo[3,4-b]quinoline Chinnakali, K. Sudha, D. Jayagobi, M. Raghunathan, R. Fun, Hoong-Kun Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(32)H(32)N(2)O(3)S, the pyrrolidine ring adopts an envelope conformation with the methine C atom nearest to the phenyl ring as the flap atom. The tetrahydropyridine ring has a half-chair conformation. The two rings are trans-fused. The phenyl ring bound to the tetrahydropyridine is oriented almost perpendicular [dihedral angle = 86.35 (10)°] to the fused benzene ring. The dihedral angle between the benzylphenyl ring and the sulfonyl-bound phenyl ring is 69.43 (10)°. A very weak N—H⋯π interaction is observed in the molecular structure. In the crystal, molecules translated one unit along the b axis are linked into C(10) chains by C—H⋯O hydrogen bonds; adjacent chains are linked via C—H⋯π interactions, forming a two-dimensional network parallel to the bc plane. International Union of Crystallography 2009-10-31 /pmc/articles/PMC2971011/ /pubmed/21578528 http://dx.doi.org/10.1107/S1600536809044973 Text en © Chinnakali et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Chinnakali, K. Sudha, D. Jayagobi, M. Raghunathan, R. Fun, Hoong-Kun 3-Benzyl-7-methoxy-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexahydro-1H-pyrrolo[3,4-b]quinoline |
title | 3-Benzyl-7-methoxy-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexahydro-1H-pyrrolo[3,4-b]quinoline |
title_full | 3-Benzyl-7-methoxy-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexahydro-1H-pyrrolo[3,4-b]quinoline |
title_fullStr | 3-Benzyl-7-methoxy-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexahydro-1H-pyrrolo[3,4-b]quinoline |
title_full_unstemmed | 3-Benzyl-7-methoxy-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexahydro-1H-pyrrolo[3,4-b]quinoline |
title_short | 3-Benzyl-7-methoxy-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexahydro-1H-pyrrolo[3,4-b]quinoline |
title_sort | 3-benzyl-7-methoxy-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexahydro-1h-pyrrolo[3,4-b]quinoline |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971011/ https://www.ncbi.nlm.nih.gov/pubmed/21578528 http://dx.doi.org/10.1107/S1600536809044973 |
work_keys_str_mv | AT chinnakalik 3benzyl7methoxy9phenyl2tosyl233a499ahexahydro1hpyrrolo34bquinoline AT sudhad 3benzyl7methoxy9phenyl2tosyl233a499ahexahydro1hpyrrolo34bquinoline AT jayagobim 3benzyl7methoxy9phenyl2tosyl233a499ahexahydro1hpyrrolo34bquinoline AT raghunathanr 3benzyl7methoxy9phenyl2tosyl233a499ahexahydro1hpyrrolo34bquinoline AT funhoongkun 3benzyl7methoxy9phenyl2tosyl233a499ahexahydro1hpyrrolo34bquinoline |