1,1′-[4-(4-Methoxy­phen­yl)-2,6-dimethyl-1,4-dihydro­pyridine-3,5-di­yl]diethanone

In the title compound, C(18)H(21)NO(3), which belongs to the family of calcium channel blockers, the dihydropyridine ring assumes a flattened boat conformation. The two carbonyl units adopt a synperiplanar conformation with respect to the double bonds in the dihydro­pyridine ring. The methoxy­phenyl...

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Autores principales: Thenmozhi, M., Kavitha, T., Reddy, B. Palakshi, Vijayakumar, V., Ponnuswamy, M. N.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971090/
https://www.ncbi.nlm.nih.gov/pubmed/21578387
http://dx.doi.org/10.1107/S1600536809041592
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author Thenmozhi, M.
Kavitha, T.
Reddy, B. Palakshi
Vijayakumar, V.
Ponnuswamy, M. N.
author_facet Thenmozhi, M.
Kavitha, T.
Reddy, B. Palakshi
Vijayakumar, V.
Ponnuswamy, M. N.
author_sort Thenmozhi, M.
collection PubMed
description In the title compound, C(18)H(21)NO(3), which belongs to the family of calcium channel blockers, the dihydropyridine ring assumes a flattened boat conformation. The two carbonyl units adopt a synperiplanar conformation with respect to the double bonds in the dihydro­pyridine ring. The methoxy­phenyl ring is almost perpendicular to the prydine ring [dihedral angle = 89.01 (7)°]. In the crystal, the mol­ecules are connected by inter­molecular N—H⋯O hydrogen bonds.
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spelling pubmed-29710902010-12-30 1,1′-[4-(4-Methoxy­phen­yl)-2,6-dimethyl-1,4-dihydro­pyridine-3,5-di­yl]diethanone Thenmozhi, M. Kavitha, T. Reddy, B. Palakshi Vijayakumar, V. Ponnuswamy, M. N. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(18)H(21)NO(3), which belongs to the family of calcium channel blockers, the dihydropyridine ring assumes a flattened boat conformation. The two carbonyl units adopt a synperiplanar conformation with respect to the double bonds in the dihydro­pyridine ring. The methoxy­phenyl ring is almost perpendicular to the prydine ring [dihedral angle = 89.01 (7)°]. In the crystal, the mol­ecules are connected by inter­molecular N—H⋯O hydrogen bonds. International Union of Crystallography 2009-10-17 /pmc/articles/PMC2971090/ /pubmed/21578387 http://dx.doi.org/10.1107/S1600536809041592 Text en © Thenmozhi et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Thenmozhi, M.
Kavitha, T.
Reddy, B. Palakshi
Vijayakumar, V.
Ponnuswamy, M. N.
1,1′-[4-(4-Methoxy­phen­yl)-2,6-dimethyl-1,4-dihydro­pyridine-3,5-di­yl]diethanone
title 1,1′-[4-(4-Methoxy­phen­yl)-2,6-dimethyl-1,4-dihydro­pyridine-3,5-di­yl]diethanone
title_full 1,1′-[4-(4-Methoxy­phen­yl)-2,6-dimethyl-1,4-dihydro­pyridine-3,5-di­yl]diethanone
title_fullStr 1,1′-[4-(4-Methoxy­phen­yl)-2,6-dimethyl-1,4-dihydro­pyridine-3,5-di­yl]diethanone
title_full_unstemmed 1,1′-[4-(4-Methoxy­phen­yl)-2,6-dimethyl-1,4-dihydro­pyridine-3,5-di­yl]diethanone
title_short 1,1′-[4-(4-Methoxy­phen­yl)-2,6-dimethyl-1,4-dihydro­pyridine-3,5-di­yl]diethanone
title_sort 1,1′-[4-(4-methoxy­phen­yl)-2,6-dimethyl-1,4-dihydro­pyridine-3,5-di­yl]diethanone
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971090/
https://www.ncbi.nlm.nih.gov/pubmed/21578387
http://dx.doi.org/10.1107/S1600536809041592
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AT reddybpalakshi 1144methoxyphenyl26dimethyl14dihydropyridine35diyldiethanone
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