(5R)-Ethyl 6-benzyl-8,8-dimethyl-7,9-dioxo-1-oxa-2,6-diaza­spiro­[4.4]non-2-ene-3-carboxyl­ate

In the title compound, C(18)H(20)N(2)O(5), the pyrrolidine ring adopts an envelope conformation with the C atom bonded to the methyl groups as the flap. The dihydro­isoxazole ring is essentially planar (r.m.s. deviation = 0.041 Å) and forms a dihedral angle of 65.19 (6)° with the phenyl ring. In the...

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Autores principales: Bathich, Yaser, Mohammat, Mohd Fazli, Hamzah, Ahmad Sazali, Goh, Jia Hao, Fun, Hoong-Kun
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971144/
https://www.ncbi.nlm.nih.gov/pubmed/21578472
http://dx.doi.org/10.1107/S1600536809042433
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author Bathich, Yaser
Mohammat, Mohd Fazli
Hamzah, Ahmad Sazali
Goh, Jia Hao
Fun, Hoong-Kun
author_facet Bathich, Yaser
Mohammat, Mohd Fazli
Hamzah, Ahmad Sazali
Goh, Jia Hao
Fun, Hoong-Kun
author_sort Bathich, Yaser
collection PubMed
description In the title compound, C(18)H(20)N(2)O(5), the pyrrolidine ring adopts an envelope conformation with the C atom bonded to the methyl groups as the flap. The dihydro­isoxazole ring is essentially planar (r.m.s. deviation = 0.041 Å) and forms a dihedral angle of 65.19 (6)° with the phenyl ring. In the crystal, neighbouring mol­ecules are linked into chains along [110] by inter­molecular C—H⋯O hydrogen bonds and weak C—H⋯π inter­actions involving the phenyl ring.
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spelling pubmed-29711442010-12-30 (5R)-Ethyl 6-benzyl-8,8-dimethyl-7,9-dioxo-1-oxa-2,6-diaza­spiro­[4.4]non-2-ene-3-carboxyl­ate Bathich, Yaser Mohammat, Mohd Fazli Hamzah, Ahmad Sazali Goh, Jia Hao Fun, Hoong-Kun Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(18)H(20)N(2)O(5), the pyrrolidine ring adopts an envelope conformation with the C atom bonded to the methyl groups as the flap. The dihydro­isoxazole ring is essentially planar (r.m.s. deviation = 0.041 Å) and forms a dihedral angle of 65.19 (6)° with the phenyl ring. In the crystal, neighbouring mol­ecules are linked into chains along [110] by inter­molecular C—H⋯O hydrogen bonds and weak C—H⋯π inter­actions involving the phenyl ring. International Union of Crystallography 2009-10-28 /pmc/articles/PMC2971144/ /pubmed/21578472 http://dx.doi.org/10.1107/S1600536809042433 Text en © Bathich et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Bathich, Yaser
Mohammat, Mohd Fazli
Hamzah, Ahmad Sazali
Goh, Jia Hao
Fun, Hoong-Kun
(5R)-Ethyl 6-benzyl-8,8-dimethyl-7,9-dioxo-1-oxa-2,6-diaza­spiro­[4.4]non-2-ene-3-carboxyl­ate
title (5R)-Ethyl 6-benzyl-8,8-dimethyl-7,9-dioxo-1-oxa-2,6-diaza­spiro­[4.4]non-2-ene-3-carboxyl­ate
title_full (5R)-Ethyl 6-benzyl-8,8-dimethyl-7,9-dioxo-1-oxa-2,6-diaza­spiro­[4.4]non-2-ene-3-carboxyl­ate
title_fullStr (5R)-Ethyl 6-benzyl-8,8-dimethyl-7,9-dioxo-1-oxa-2,6-diaza­spiro­[4.4]non-2-ene-3-carboxyl­ate
title_full_unstemmed (5R)-Ethyl 6-benzyl-8,8-dimethyl-7,9-dioxo-1-oxa-2,6-diaza­spiro­[4.4]non-2-ene-3-carboxyl­ate
title_short (5R)-Ethyl 6-benzyl-8,8-dimethyl-7,9-dioxo-1-oxa-2,6-diaza­spiro­[4.4]non-2-ene-3-carboxyl­ate
title_sort (5r)-ethyl 6-benzyl-8,8-dimethyl-7,9-dioxo-1-oxa-2,6-diaza­spiro­[4.4]non-2-ene-3-carboxyl­ate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971144/
https://www.ncbi.nlm.nih.gov/pubmed/21578472
http://dx.doi.org/10.1107/S1600536809042433
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