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(5-Ethenyl-1-aza­bicyclo­[2.2.2]octan-2-yl)(6-meth­oxy-3-quinol­yl)methanol methanol solvate

In the title methanol solvate, C(20)H(24)N(2)O(2)·CH(4)O, an L-shaped conformation is found as the two substituents at the central hydr­oxy group are almost orthogonal to each other [the C—C—C angle at the central sp (3)-C atom is 110.12 (13)°]. The most notable feature of the crystal packing is the...

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Detalles Bibliográficos
Autores principales: Muramulla, Savitha, Arman, Hadi D., Zhao, Cong-Gui, Tiekink, Edward R. T.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971146/
https://www.ncbi.nlm.nih.gov/pubmed/21578533
http://dx.doi.org/10.1107/S1600536809045073
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author Muramulla, Savitha
Arman, Hadi D.
Zhao, Cong-Gui
Tiekink, Edward R. T.
author_facet Muramulla, Savitha
Arman, Hadi D.
Zhao, Cong-Gui
Tiekink, Edward R. T.
author_sort Muramulla, Savitha
collection PubMed
description In the title methanol solvate, C(20)H(24)N(2)O(2)·CH(4)O, an L-shaped conformation is found as the two substituents at the central hydr­oxy group are almost orthogonal to each other [the C—C—C angle at the central sp (3)-C atom is 110.12 (13)°]. The most notable feature of the crystal packing is the formation of supra­molecular chains along the b direction mediated by O—H⋯N hydrogen bonds occurring between the hydr­oxy and quinoline N atoms; the methanol mol­ecules are linked to these chains via O—H⋯N(amine) hydrogen bonds. C—H⋯O inter­actions also occur.
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spelling pubmed-29711462010-12-30 (5-Ethenyl-1-aza­bicyclo­[2.2.2]octan-2-yl)(6-meth­oxy-3-quinol­yl)methanol methanol solvate Muramulla, Savitha Arman, Hadi D. Zhao, Cong-Gui Tiekink, Edward R. T. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title methanol solvate, C(20)H(24)N(2)O(2)·CH(4)O, an L-shaped conformation is found as the two substituents at the central hydr­oxy group are almost orthogonal to each other [the C—C—C angle at the central sp (3)-C atom is 110.12 (13)°]. The most notable feature of the crystal packing is the formation of supra­molecular chains along the b direction mediated by O—H⋯N hydrogen bonds occurring between the hydr­oxy and quinoline N atoms; the methanol mol­ecules are linked to these chains via O—H⋯N(amine) hydrogen bonds. C—H⋯O inter­actions also occur. International Union of Crystallography 2009-10-31 /pmc/articles/PMC2971146/ /pubmed/21578533 http://dx.doi.org/10.1107/S1600536809045073 Text en © Muramulla et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Muramulla, Savitha
Arman, Hadi D.
Zhao, Cong-Gui
Tiekink, Edward R. T.
(5-Ethenyl-1-aza­bicyclo­[2.2.2]octan-2-yl)(6-meth­oxy-3-quinol­yl)methanol methanol solvate
title (5-Ethenyl-1-aza­bicyclo­[2.2.2]octan-2-yl)(6-meth­oxy-3-quinol­yl)methanol methanol solvate
title_full (5-Ethenyl-1-aza­bicyclo­[2.2.2]octan-2-yl)(6-meth­oxy-3-quinol­yl)methanol methanol solvate
title_fullStr (5-Ethenyl-1-aza­bicyclo­[2.2.2]octan-2-yl)(6-meth­oxy-3-quinol­yl)methanol methanol solvate
title_full_unstemmed (5-Ethenyl-1-aza­bicyclo­[2.2.2]octan-2-yl)(6-meth­oxy-3-quinol­yl)methanol methanol solvate
title_short (5-Ethenyl-1-aza­bicyclo­[2.2.2]octan-2-yl)(6-meth­oxy-3-quinol­yl)methanol methanol solvate
title_sort (5-ethenyl-1-aza­bicyclo­[2.2.2]octan-2-yl)(6-meth­oxy-3-quinol­yl)methanol methanol solvate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971146/
https://www.ncbi.nlm.nih.gov/pubmed/21578533
http://dx.doi.org/10.1107/S1600536809045073
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AT zhaoconggui 5ethenyl1azabicyclo222octan2yl6methoxy3quinolylmethanolmethanolsolvate
AT tiekinkedwardrt 5ethenyl1azabicyclo222octan2yl6methoxy3quinolylmethanolmethanolsolvate