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(5-Ethenyl-1-azabicyclo[2.2.2]octan-2-yl)(6-methoxy-3-quinolyl)methanol methanol solvate
In the title methanol solvate, C(20)H(24)N(2)O(2)·CH(4)O, an L-shaped conformation is found as the two substituents at the central hydroxy group are almost orthogonal to each other [the C—C—C angle at the central sp (3)-C atom is 110.12 (13)°]. The most notable feature of the crystal packing is the...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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International Union of Crystallography
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971146/ https://www.ncbi.nlm.nih.gov/pubmed/21578533 http://dx.doi.org/10.1107/S1600536809045073 |
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author | Muramulla, Savitha Arman, Hadi D. Zhao, Cong-Gui Tiekink, Edward R. T. |
author_facet | Muramulla, Savitha Arman, Hadi D. Zhao, Cong-Gui Tiekink, Edward R. T. |
author_sort | Muramulla, Savitha |
collection | PubMed |
description | In the title methanol solvate, C(20)H(24)N(2)O(2)·CH(4)O, an L-shaped conformation is found as the two substituents at the central hydroxy group are almost orthogonal to each other [the C—C—C angle at the central sp (3)-C atom is 110.12 (13)°]. The most notable feature of the crystal packing is the formation of supramolecular chains along the b direction mediated by O—H⋯N hydrogen bonds occurring between the hydroxy and quinoline N atoms; the methanol molecules are linked to these chains via O—H⋯N(amine) hydrogen bonds. C—H⋯O interactions also occur. |
format | Text |
id | pubmed-2971146 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-29711462010-12-30 (5-Ethenyl-1-azabicyclo[2.2.2]octan-2-yl)(6-methoxy-3-quinolyl)methanol methanol solvate Muramulla, Savitha Arman, Hadi D. Zhao, Cong-Gui Tiekink, Edward R. T. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title methanol solvate, C(20)H(24)N(2)O(2)·CH(4)O, an L-shaped conformation is found as the two substituents at the central hydroxy group are almost orthogonal to each other [the C—C—C angle at the central sp (3)-C atom is 110.12 (13)°]. The most notable feature of the crystal packing is the formation of supramolecular chains along the b direction mediated by O—H⋯N hydrogen bonds occurring between the hydroxy and quinoline N atoms; the methanol molecules are linked to these chains via O—H⋯N(amine) hydrogen bonds. C—H⋯O interactions also occur. International Union of Crystallography 2009-10-31 /pmc/articles/PMC2971146/ /pubmed/21578533 http://dx.doi.org/10.1107/S1600536809045073 Text en © Muramulla et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Muramulla, Savitha Arman, Hadi D. Zhao, Cong-Gui Tiekink, Edward R. T. (5-Ethenyl-1-azabicyclo[2.2.2]octan-2-yl)(6-methoxy-3-quinolyl)methanol methanol solvate |
title | (5-Ethenyl-1-azabicyclo[2.2.2]octan-2-yl)(6-methoxy-3-quinolyl)methanol methanol solvate |
title_full | (5-Ethenyl-1-azabicyclo[2.2.2]octan-2-yl)(6-methoxy-3-quinolyl)methanol methanol solvate |
title_fullStr | (5-Ethenyl-1-azabicyclo[2.2.2]octan-2-yl)(6-methoxy-3-quinolyl)methanol methanol solvate |
title_full_unstemmed | (5-Ethenyl-1-azabicyclo[2.2.2]octan-2-yl)(6-methoxy-3-quinolyl)methanol methanol solvate |
title_short | (5-Ethenyl-1-azabicyclo[2.2.2]octan-2-yl)(6-methoxy-3-quinolyl)methanol methanol solvate |
title_sort | (5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl)(6-methoxy-3-quinolyl)methanol methanol solvate |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971146/ https://www.ncbi.nlm.nih.gov/pubmed/21578533 http://dx.doi.org/10.1107/S1600536809045073 |
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