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1-Formyl-r-2,c-6-bis(4-methoxyphenyl)-t-3-methylpiperidin-4-one
The asymmetric unit of the title compound, C(21)H(23)NO(4), contains two crystallographically independent molecules A and B. In both molecules, the piperidine-4-one rings adopt a distorted twist-boat conformation. The formyl group at position 1, the methoxyphenyl ring at position 2 and the methyl...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971181/ https://www.ncbi.nlm.nih.gov/pubmed/21578404 http://dx.doi.org/10.1107/S1600536809042457 |
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author | Gayathri, P. Sakthivel, P. Ponnuswamy, S. Thiruvalluvar, A. Butcher, R. J. |
author_facet | Gayathri, P. Sakthivel, P. Ponnuswamy, S. Thiruvalluvar, A. Butcher, R. J. |
author_sort | Gayathri, P. |
collection | PubMed |
description | The asymmetric unit of the title compound, C(21)H(23)NO(4), contains two crystallographically independent molecules A and B. In both molecules, the piperidine-4-one rings adopt a distorted twist-boat conformation. The formyl group at position 1, the methoxyphenyl ring at position 2 and the methyl group at position 3 are attached equatorially. The methoxy phenyl ring at position 6 has an axial orientation. The dihedral angle between the two benzene rings is 55.27 (8)° in molecule A, and 55.29 (8)° in molecule B. In the crystal, the molecules are linked by weak C—H⋯O intermolecular hydrogen-bond interactions. In addition, weak C—H⋯π intermolecular interactions involving the benzene rings at positions 6 and 2 of molecule B are also found in the crystal structure. |
format | Text |
id | pubmed-2971181 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-29711812010-12-30 1-Formyl-r-2,c-6-bis(4-methoxyphenyl)-t-3-methylpiperidin-4-one Gayathri, P. Sakthivel, P. Ponnuswamy, S. Thiruvalluvar, A. Butcher, R. J. Acta Crystallogr Sect E Struct Rep Online Organic Papers The asymmetric unit of the title compound, C(21)H(23)NO(4), contains two crystallographically independent molecules A and B. In both molecules, the piperidine-4-one rings adopt a distorted twist-boat conformation. The formyl group at position 1, the methoxyphenyl ring at position 2 and the methyl group at position 3 are attached equatorially. The methoxy phenyl ring at position 6 has an axial orientation. The dihedral angle between the two benzene rings is 55.27 (8)° in molecule A, and 55.29 (8)° in molecule B. In the crystal, the molecules are linked by weak C—H⋯O intermolecular hydrogen-bond interactions. In addition, weak C—H⋯π intermolecular interactions involving the benzene rings at positions 6 and 2 of molecule B are also found in the crystal structure. International Union of Crystallography 2009-10-23 /pmc/articles/PMC2971181/ /pubmed/21578404 http://dx.doi.org/10.1107/S1600536809042457 Text en © Gayathri et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Gayathri, P. Sakthivel, P. Ponnuswamy, S. Thiruvalluvar, A. Butcher, R. J. 1-Formyl-r-2,c-6-bis(4-methoxyphenyl)-t-3-methylpiperidin-4-one |
title | 1-Formyl-r-2,c-6-bis(4-methoxyphenyl)-t-3-methylpiperidin-4-one |
title_full | 1-Formyl-r-2,c-6-bis(4-methoxyphenyl)-t-3-methylpiperidin-4-one |
title_fullStr | 1-Formyl-r-2,c-6-bis(4-methoxyphenyl)-t-3-methylpiperidin-4-one |
title_full_unstemmed | 1-Formyl-r-2,c-6-bis(4-methoxyphenyl)-t-3-methylpiperidin-4-one |
title_short | 1-Formyl-r-2,c-6-bis(4-methoxyphenyl)-t-3-methylpiperidin-4-one |
title_sort | 1-formyl-r-2,c-6-bis(4-methoxyphenyl)-t-3-methylpiperidin-4-one |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971181/ https://www.ncbi.nlm.nih.gov/pubmed/21578404 http://dx.doi.org/10.1107/S1600536809042457 |
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