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3-Benzyl-7-methyl-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexahydro-1H-pyrrolo[3,4-b]quinoline
In the title compound, C(32)H(32)N(2)O(2)S, the pyrrolidine ring adopts a twist conformation while the tetrahydropyridine ring is in a distorted half-chair conformation. The two rings are trans-fused. The dihedral angle between the sulfonyl and benzyl phenyl rings is 72.54 (14)°. The molecular st...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971294/ https://www.ncbi.nlm.nih.gov/pubmed/21578502 http://dx.doi.org/10.1107/S1600536809044481 |
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author | Chinnakali, K. Sudha, D. Jayagobi, M. Raghunathan, R. Fun, Hoong-Kun |
author_facet | Chinnakali, K. Sudha, D. Jayagobi, M. Raghunathan, R. Fun, Hoong-Kun |
author_sort | Chinnakali, K. |
collection | PubMed |
description | In the title compound, C(32)H(32)N(2)O(2)S, the pyrrolidine ring adopts a twist conformation while the tetrahydropyridine ring is in a distorted half-chair conformation. The two rings are trans-fused. The dihedral angle between the sulfonyl and benzyl phenyl rings is 72.54 (14)°. The molecular structure is stabilized by C—H⋯O hydrogen bonds, and N—H⋯π interactions involving the benzyl phenyl ring. The screw-related molecules are linked into chains along the b axis by C—H⋯O hydrogen bonds and C—H⋯π interactions. Adjacent inversion-related chains interact via C—H⋯π interactions, forming a two-dimensional network parallel to the bc plane. |
format | Text |
id | pubmed-2971294 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-29712942010-12-30 3-Benzyl-7-methyl-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexahydro-1H-pyrrolo[3,4-b]quinoline Chinnakali, K. Sudha, D. Jayagobi, M. Raghunathan, R. Fun, Hoong-Kun Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(32)H(32)N(2)O(2)S, the pyrrolidine ring adopts a twist conformation while the tetrahydropyridine ring is in a distorted half-chair conformation. The two rings are trans-fused. The dihedral angle between the sulfonyl and benzyl phenyl rings is 72.54 (14)°. The molecular structure is stabilized by C—H⋯O hydrogen bonds, and N—H⋯π interactions involving the benzyl phenyl ring. The screw-related molecules are linked into chains along the b axis by C—H⋯O hydrogen bonds and C—H⋯π interactions. Adjacent inversion-related chains interact via C—H⋯π interactions, forming a two-dimensional network parallel to the bc plane. International Union of Crystallography 2009-10-31 /pmc/articles/PMC2971294/ /pubmed/21578502 http://dx.doi.org/10.1107/S1600536809044481 Text en © Chinnakali et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Chinnakali, K. Sudha, D. Jayagobi, M. Raghunathan, R. Fun, Hoong-Kun 3-Benzyl-7-methyl-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexahydro-1H-pyrrolo[3,4-b]quinoline |
title | 3-Benzyl-7-methyl-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexahydro-1H-pyrrolo[3,4-b]quinoline |
title_full | 3-Benzyl-7-methyl-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexahydro-1H-pyrrolo[3,4-b]quinoline |
title_fullStr | 3-Benzyl-7-methyl-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexahydro-1H-pyrrolo[3,4-b]quinoline |
title_full_unstemmed | 3-Benzyl-7-methyl-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexahydro-1H-pyrrolo[3,4-b]quinoline |
title_short | 3-Benzyl-7-methyl-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexahydro-1H-pyrrolo[3,4-b]quinoline |
title_sort | 3-benzyl-7-methyl-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexahydro-1h-pyrrolo[3,4-b]quinoline |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971294/ https://www.ncbi.nlm.nih.gov/pubmed/21578502 http://dx.doi.org/10.1107/S1600536809044481 |
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