N,N-Dicyclo­hexyl-2-(5,7-dichloro-8-quinol­yloxy)acetamide

The mol­ecular and crystal structures of the title compound, C(23)H(28)Cl(2)N(2)O(2), are very close to those of the bromine-substituted analogue N,N-dicyclo­hexyl-2-(5,7-dibromo-8-quinol­yloxy)acetamide. The two cyclo­hexyl groups adopt normal chair conformation. The amide N and C atoms have a plan...

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Detalles Bibliográficos
Autor principal: Wang, Jing-Lin
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971332/
https://www.ncbi.nlm.nih.gov/pubmed/21578274
http://dx.doi.org/10.1107/S160053680903966X
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author Wang, Jing-Lin
author_facet Wang, Jing-Lin
author_sort Wang, Jing-Lin
collection PubMed
description The mol­ecular and crystal structures of the title compound, C(23)H(28)Cl(2)N(2)O(2), are very close to those of the bromine-substituted analogue N,N-dicyclo­hexyl-2-(5,7-dibromo-8-quinol­yloxy)acetamide. The two cyclo­hexyl groups adopt normal chair conformation. The amide N and C atoms have a planar configuration. The crystal packing is stabilized by inter­molecular C—H⋯O hydrogen bonds and aromatic π⋯π stacking inter­actions [centroid–centroid separation = 3.5715 (4) Å for symmetry-related pyridine rings]. In addition, the crystal structure exhibits Cl⋯Cl halogen contacts of 3.4675 (3) Å.
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spelling pubmed-29713322010-12-30 N,N-Dicyclo­hexyl-2-(5,7-dichloro-8-quinol­yloxy)acetamide Wang, Jing-Lin Acta Crystallogr Sect E Struct Rep Online Organic Papers The mol­ecular and crystal structures of the title compound, C(23)H(28)Cl(2)N(2)O(2), are very close to those of the bromine-substituted analogue N,N-dicyclo­hexyl-2-(5,7-dibromo-8-quinol­yloxy)acetamide. The two cyclo­hexyl groups adopt normal chair conformation. The amide N and C atoms have a planar configuration. The crystal packing is stabilized by inter­molecular C—H⋯O hydrogen bonds and aromatic π⋯π stacking inter­actions [centroid–centroid separation = 3.5715 (4) Å for symmetry-related pyridine rings]. In addition, the crystal structure exhibits Cl⋯Cl halogen contacts of 3.4675 (3) Å. International Union of Crystallography 2009-10-07 /pmc/articles/PMC2971332/ /pubmed/21578274 http://dx.doi.org/10.1107/S160053680903966X Text en © Jing-Lin Wang 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Wang, Jing-Lin
N,N-Dicyclo­hexyl-2-(5,7-dichloro-8-quinol­yloxy)acetamide
title N,N-Dicyclo­hexyl-2-(5,7-dichloro-8-quinol­yloxy)acetamide
title_full N,N-Dicyclo­hexyl-2-(5,7-dichloro-8-quinol­yloxy)acetamide
title_fullStr N,N-Dicyclo­hexyl-2-(5,7-dichloro-8-quinol­yloxy)acetamide
title_full_unstemmed N,N-Dicyclo­hexyl-2-(5,7-dichloro-8-quinol­yloxy)acetamide
title_short N,N-Dicyclo­hexyl-2-(5,7-dichloro-8-quinol­yloxy)acetamide
title_sort n,n-dicyclo­hexyl-2-(5,7-dichloro-8-quinol­yloxy)acetamide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971332/
https://www.ncbi.nlm.nih.gov/pubmed/21578274
http://dx.doi.org/10.1107/S160053680903966X
work_keys_str_mv AT wangjinglin nndicyclohexyl257dichloro8quinolyloxyacetamide

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