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Mandatory fortification with folic acid in the United States appears to have adverse effects on histone methylation in women with pre-cancer but not in women free of pre-cancer
OBJECTIVE: To evaluate whether mandatory fortification of grain products with folic acid in the US is associated with changes in histone methylation in cells involved in cervical carcinogenesis. METHODS: Cervical specimens obtained before (1990 to 1992) and after mandatory folic acid fortification (...
Autores principales: | Piyathilake, Chandrika J, Macaluso, Maurizio, Celedonio, Jorge E, Badiga, Suguna, Bell, Walter C, Grizzle, William E |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971712/ https://www.ncbi.nlm.nih.gov/pubmed/21072283 |
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