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3-(2-Amino-1,3-thiazol-4-yl)-6-bromo-2H-chromen-2-one
The molecule of the title compound, C(12)H(7)BrN(2)O(2)S, is essentially planar with a maximum deviation of 0.234 (3) Å from the mean plane through all non-H atoms. The dihedral angle between the coumarin ring plane and that of the five-membered thiazole ring is 12.9 (1)°. In the crystal, strong N...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971769/ https://www.ncbi.nlm.nih.gov/pubmed/21578780 http://dx.doi.org/10.1107/S1600536809046674 |
Sumario: | The molecule of the title compound, C(12)H(7)BrN(2)O(2)S, is essentially planar with a maximum deviation of 0.234 (3) Å from the mean plane through all non-H atoms. The dihedral angle between the coumarin ring plane and that of the five-membered thiazole ring is 12.9 (1)°. In the crystal, strong N—H⋯O, N—H⋯N and weak but highly directional C—H⋯O hydrogen bonds provide the links between the molecules. In addition, C—H⋯π and π–π interactions [centroid–centroid distances = 3.950 (3)–4.024 (3) Å] provide additional stability to the interlayer regions in the lattice. |
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