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Mutual prodrug of cephazolin and benzydamin: 3-[(1-benzyl-1H-indazol-3-yl)oxy]-N,N-dimethylpropan-1-aminium 3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]octane-2-carboxylate (benzydaminium cephazolinate)
In the crystal of the title molecular salt, C(19)H(24)N(3)O(+)·C(14)H(13)N(8)O(4)S(3) (−), the cations and anions are linked by N—H⋯O hydrogen bonds. Short intramolecular C—H⋯O contacts occur within the anion and intermolecular C—H⋯O and C—H⋯π bonds help to establish the packing....
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971840/ https://www.ncbi.nlm.nih.gov/pubmed/21578855 http://dx.doi.org/10.1107/S1600536809047941 |