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2-Iodo-3-methoxy-6-methylpyridine
The title compound, C(7)H(8)INO, which crystallizes with three independent molecules in the asymmetric unit, was prepared by the reaction of 3-methoxy-6-methylpyridine with KI and I(2) in tetrahydrofuran solution. In the crystal structure, the three independent molecules are arranged in a simi...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971865/ https://www.ncbi.nlm.nih.gov/pubmed/21578963 http://dx.doi.org/10.1107/S1600536809050739 |
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author | Guo, Wenbo Liu, Xueqin Li, Long Deng, Dongsheng |
author_facet | Guo, Wenbo Liu, Xueqin Li, Long Deng, Dongsheng |
author_sort | Guo, Wenbo |
collection | PubMed |
description | The title compound, C(7)H(8)INO, which crystallizes with three independent molecules in the asymmetric unit, was prepared by the reaction of 3-methoxy-6-methylpyridine with KI and I(2) in tetrahydrofuran solution. In the crystal structure, the three independent molecules are arranged in a similar orientation with the three polar methoxy groups aligned on one side and the three non-polar methyl groups on the other side. The three molecules, excluding methyl H atoms, are essentially planar, with r.m.s. deviations of 0.0141 (1), 0.0081 (1) and 0.0066 (2)Å. The three pyridine rings make dihedral angles of 58.09 (3) 66.64 (4) and 71.5 (3)°. The crystal structure features rather weak intermolecular C—H⋯O hydrogen bonds, which link two molecules into dimers, and short I⋯N contacts [4.046 (3) Å]. |
format | Text |
id | pubmed-2971865 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-29718652010-12-30 2-Iodo-3-methoxy-6-methylpyridine Guo, Wenbo Liu, Xueqin Li, Long Deng, Dongsheng Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(7)H(8)INO, which crystallizes with three independent molecules in the asymmetric unit, was prepared by the reaction of 3-methoxy-6-methylpyridine with KI and I(2) in tetrahydrofuran solution. In the crystal structure, the three independent molecules are arranged in a similar orientation with the three polar methoxy groups aligned on one side and the three non-polar methyl groups on the other side. The three molecules, excluding methyl H atoms, are essentially planar, with r.m.s. deviations of 0.0141 (1), 0.0081 (1) and 0.0066 (2)Å. The three pyridine rings make dihedral angles of 58.09 (3) 66.64 (4) and 71.5 (3)°. The crystal structure features rather weak intermolecular C—H⋯O hydrogen bonds, which link two molecules into dimers, and short I⋯N contacts [4.046 (3) Å]. International Union of Crystallography 2009-11-28 /pmc/articles/PMC2971865/ /pubmed/21578963 http://dx.doi.org/10.1107/S1600536809050739 Text en © Guo et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Guo, Wenbo Liu, Xueqin Li, Long Deng, Dongsheng 2-Iodo-3-methoxy-6-methylpyridine |
title | 2-Iodo-3-methoxy-6-methylpyridine |
title_full | 2-Iodo-3-methoxy-6-methylpyridine |
title_fullStr | 2-Iodo-3-methoxy-6-methylpyridine |
title_full_unstemmed | 2-Iodo-3-methoxy-6-methylpyridine |
title_short | 2-Iodo-3-methoxy-6-methylpyridine |
title_sort | 2-iodo-3-methoxy-6-methylpyridine |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971865/ https://www.ncbi.nlm.nih.gov/pubmed/21578963 http://dx.doi.org/10.1107/S1600536809050739 |
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