Cargando…

2-Iodo-3-meth­oxy-6-methyl­pyridine

The title compound, C(7)H(8)INO, which crystallizes with three independent mol­ecules in the asymmetric unit, was prepared by the reaction of 3-meth­oxy-6-methyl­pyridine with KI and I(2) in tetra­hydro­furan solution. In the crystal structure, the three independent mol­ecules are arranged in a simi...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Wenbo, Liu, Xueqin, Li, Long, Deng, Dongsheng
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971865/
https://www.ncbi.nlm.nih.gov/pubmed/21578963
http://dx.doi.org/10.1107/S1600536809050739
_version_ 1782190687899353088
author Guo, Wenbo
Liu, Xueqin
Li, Long
Deng, Dongsheng
author_facet Guo, Wenbo
Liu, Xueqin
Li, Long
Deng, Dongsheng
author_sort Guo, Wenbo
collection PubMed
description The title compound, C(7)H(8)INO, which crystallizes with three independent mol­ecules in the asymmetric unit, was prepared by the reaction of 3-meth­oxy-6-methyl­pyridine with KI and I(2) in tetra­hydro­furan solution. In the crystal structure, the three independent mol­ecules are arranged in a similar orientation with the three polar meth­oxy groups aligned on one side and the three non-polar methyl groups on the other side. The three mol­ecules, excluding methyl H atoms, are essentially planar, with r.m.s. deviations of 0.0141 (1), 0.0081 (1) and 0.0066 (2)Å. The three pyridine rings make dihedral angles of 58.09 (3) 66.64 (4) and 71.5 (3)°. The crystal structure features rather weak inter­molecular C—H⋯O hydrogen bonds, which link two mol­ecules into dimers, and short I⋯N contacts [4.046 (3) Å].
format Text
id pubmed-2971865
institution National Center for Biotechnology Information
language English
publishDate 2009
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-29718652010-12-30 2-Iodo-3-meth­oxy-6-methyl­pyridine Guo, Wenbo Liu, Xueqin Li, Long Deng, Dongsheng Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(7)H(8)INO, which crystallizes with three independent mol­ecules in the asymmetric unit, was prepared by the reaction of 3-meth­oxy-6-methyl­pyridine with KI and I(2) in tetra­hydro­furan solution. In the crystal structure, the three independent mol­ecules are arranged in a similar orientation with the three polar meth­oxy groups aligned on one side and the three non-polar methyl groups on the other side. The three mol­ecules, excluding methyl H atoms, are essentially planar, with r.m.s. deviations of 0.0141 (1), 0.0081 (1) and 0.0066 (2)Å. The three pyridine rings make dihedral angles of 58.09 (3) 66.64 (4) and 71.5 (3)°. The crystal structure features rather weak inter­molecular C—H⋯O hydrogen bonds, which link two mol­ecules into dimers, and short I⋯N contacts [4.046 (3) Å]. International Union of Crystallography 2009-11-28 /pmc/articles/PMC2971865/ /pubmed/21578963 http://dx.doi.org/10.1107/S1600536809050739 Text en © Guo et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Guo, Wenbo
Liu, Xueqin
Li, Long
Deng, Dongsheng
2-Iodo-3-meth­oxy-6-methyl­pyridine
title 2-Iodo-3-meth­oxy-6-methyl­pyridine
title_full 2-Iodo-3-meth­oxy-6-methyl­pyridine
title_fullStr 2-Iodo-3-meth­oxy-6-methyl­pyridine
title_full_unstemmed 2-Iodo-3-meth­oxy-6-methyl­pyridine
title_short 2-Iodo-3-meth­oxy-6-methyl­pyridine
title_sort 2-iodo-3-meth­oxy-6-methyl­pyridine
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971865/
https://www.ncbi.nlm.nih.gov/pubmed/21578963
http://dx.doi.org/10.1107/S1600536809050739
work_keys_str_mv AT guowenbo 2iodo3methoxy6methylpyridine
AT liuxueqin 2iodo3methoxy6methylpyridine
AT lilong 2iodo3methoxy6methylpyridine
AT dengdongsheng 2iodo3methoxy6methylpyridine