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Ethyl 4-hydroxy-1-(2-morpholinopropanoyl)-2,6-diphenyl-1,2,5,6-tetrahydropyridin-3-carboxylate
In the title compound, C(27)H(32)N(2)O(5), the morpholine ring adopts a chair conformation with two C atoms deviating by −0.656 (4) and 0.679 (3) Å from the least-squares plane defined by the rest of atoms in the ring. The tetrahydropyridine ring adopts a half-chair conformation. The molecular st...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971963/ https://www.ncbi.nlm.nih.gov/pubmed/21578938 http://dx.doi.org/10.1107/S1600536809050259 |
| _version_ | 1782190711419961344 |
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| author | Aridoss, G. Gayathri, D. Ramachandran, R. Lim, Kwon Taek Jeong, Yeon Tae |
| author_facet | Aridoss, G. Gayathri, D. Ramachandran, R. Lim, Kwon Taek Jeong, Yeon Tae |
| author_sort | Aridoss, G. |
| collection | PubMed |
| description | In the title compound, C(27)H(32)N(2)O(5), the morpholine ring adopts a chair conformation with two C atoms deviating by −0.656 (4) and 0.679 (3) Å from the least-squares plane defined by the rest of atoms in the ring. The tetrahydropyridine ring adopts a half-chair conformation. The molecular structure is stabilized by a strong intramolecular O—H⋯O interaction, generating an S(6) motif. The crystal packing is stabilized by intermolecular C—H⋯O interactions, generating a C(7) chain along the a axis, and R (2) (2)(20) and R (4) (4)(20) graph-set motifs. |
| format | Text |
| id | pubmed-2971963 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2009 |
| publisher | International Union of Crystallography |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-29719632010-12-30 Ethyl 4-hydroxy-1-(2-morpholinopropanoyl)-2,6-diphenyl-1,2,5,6-tetrahydropyridin-3-carboxylate Aridoss, G. Gayathri, D. Ramachandran, R. Lim, Kwon Taek Jeong, Yeon Tae Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(27)H(32)N(2)O(5), the morpholine ring adopts a chair conformation with two C atoms deviating by −0.656 (4) and 0.679 (3) Å from the least-squares plane defined by the rest of atoms in the ring. The tetrahydropyridine ring adopts a half-chair conformation. The molecular structure is stabilized by a strong intramolecular O—H⋯O interaction, generating an S(6) motif. The crystal packing is stabilized by intermolecular C—H⋯O interactions, generating a C(7) chain along the a axis, and R (2) (2)(20) and R (4) (4)(20) graph-set motifs. International Union of Crystallography 2009-11-28 /pmc/articles/PMC2971963/ /pubmed/21578938 http://dx.doi.org/10.1107/S1600536809050259 Text en © Aridoss et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
| spellingShingle | Organic Papers Aridoss, G. Gayathri, D. Ramachandran, R. Lim, Kwon Taek Jeong, Yeon Tae Ethyl 4-hydroxy-1-(2-morpholinopropanoyl)-2,6-diphenyl-1,2,5,6-tetrahydropyridin-3-carboxylate |
| title | Ethyl 4-hydroxy-1-(2-morpholinopropanoyl)-2,6-diphenyl-1,2,5,6-tetrahydropyridin-3-carboxylate |
| title_full | Ethyl 4-hydroxy-1-(2-morpholinopropanoyl)-2,6-diphenyl-1,2,5,6-tetrahydropyridin-3-carboxylate |
| title_fullStr | Ethyl 4-hydroxy-1-(2-morpholinopropanoyl)-2,6-diphenyl-1,2,5,6-tetrahydropyridin-3-carboxylate |
| title_full_unstemmed | Ethyl 4-hydroxy-1-(2-morpholinopropanoyl)-2,6-diphenyl-1,2,5,6-tetrahydropyridin-3-carboxylate |
| title_short | Ethyl 4-hydroxy-1-(2-morpholinopropanoyl)-2,6-diphenyl-1,2,5,6-tetrahydropyridin-3-carboxylate |
| title_sort | ethyl 4-hydroxy-1-(2-morpholinopropanoyl)-2,6-diphenyl-1,2,5,6-tetrahydropyridin-3-carboxylate |
| topic | Organic Papers |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971963/ https://www.ncbi.nlm.nih.gov/pubmed/21578938 http://dx.doi.org/10.1107/S1600536809050259 |
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