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1-(3-p-Tolyl­isoxazol-5-yl)cyclo­hexa­nol

The title compound, C(16)H(19)NO(2), contains two mol­ecules in the asymmetric unit. Each mol­ecule is composed of three inter­connected rings, two essentially planar rings, viz. the isoxazole and the methyl­benzyl aromatic ring [maximum deviations of 0.0027 (13) and 0.0031 (19) Å from the isoxazole...

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Detalles Bibliográficos
Autores principales: Khalil, Ouafaa, Bougrin, Khalid, Benhida, Rachid, Soufiaoui, Mohamed, Ammari, Lahcen El
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972041/
https://www.ncbi.nlm.nih.gov/pubmed/21578712
http://dx.doi.org/10.1107/S1600536809044900
Descripción
Sumario:The title compound, C(16)H(19)NO(2), contains two mol­ecules in the asymmetric unit. Each mol­ecule is composed of three inter­connected rings, two essentially planar rings, viz. the isoxazole and the methyl­benzyl aromatic ring [maximum deviations of 0.0027 (13) and 0.0031 (19) Å from the isoxazole and methylbenzyl ring planes, respectively, in the first molecule, 0.0018 (12) and 0.019 (2) Å in the second molecule], and one cyclo­hexa­nol ring having a chair conformation. Although the two mol­ecules have similar bond distances and angles, they differ in the orientation of the cyclo­hexa­nol ring with respect to the tolyl­isoxazole unit. In the first mol­ecule, the dihedral angle between the isoxazole and methyl­benzyl rings is 22.03 (8)° and between the isoxazole and cyclo­hexa­nol rings is 30.15 (8)°. The corresponding values in the second mol­ecule are 6.13 (10) and 88.44 (8)°, respectively. In the crystal, the molecules are linked by O—H⋯O and O—H⋯N hydrogen bonds, building up a zigzag chain parallel to the a axis.