N-{4-[4-(4-Fluoro­phen­yl)-1-(2-methoxy­ethyl)-2-methyl­sulfanyl-1H-imidazol-5-yl]-2-pyrid­yl}-2-methyl-3-phenyl­propionamide

In the crystal structure of the title compound, C(28)H(29)FN(4)O(2)S, the imidazole ring makes dihedral angles of 11.85 (7), 73.33 (7) and 22.83 (8)° with the 4-fluoro­phenyl, pyridine and phenyl rings, respectively. The 4-fluoro­phenyl ring makes dihedral angles of 77.91 (7) and 26.93 (8)° with the...

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Detalles Bibliográficos
Autores principales: Ziegler, Katharina, Schollmeyer, Dieter, Laufer, Stefan
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972069/
https://www.ncbi.nlm.nih.gov/pubmed/21578851
http://dx.doi.org/10.1107/S1600536809048661
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author Ziegler, Katharina
Schollmeyer, Dieter
Laufer, Stefan
author_facet Ziegler, Katharina
Schollmeyer, Dieter
Laufer, Stefan
author_sort Ziegler, Katharina
collection PubMed
description In the crystal structure of the title compound, C(28)H(29)FN(4)O(2)S, the imidazole ring makes dihedral angles of 11.85 (7), 73.33 (7) and 22.83 (8)° with the 4-fluoro­phenyl, pyridine and phenyl rings, respectively. The 4-fluoro­phenyl ring makes dihedral angles of 77.91 (7) and 26.93 (8)° with the pyridine and phenyl rings, respectively. The phenyl and pyridine rings are nearly perpendicular, making a dihedral angle of 86.47 (9)°. The crystal packing shows an inter­molecular N—H⋯O hydrogen-bonding inter­action between the N—H and carbonyl groups of the amide functions.
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spelling pubmed-29720692010-12-30 N-{4-[4-(4-Fluoro­phen­yl)-1-(2-methoxy­ethyl)-2-methyl­sulfanyl-1H-imidazol-5-yl]-2-pyrid­yl}-2-methyl-3-phenyl­propionamide Ziegler, Katharina Schollmeyer, Dieter Laufer, Stefan Acta Crystallogr Sect E Struct Rep Online Organic Papers In the crystal structure of the title compound, C(28)H(29)FN(4)O(2)S, the imidazole ring makes dihedral angles of 11.85 (7), 73.33 (7) and 22.83 (8)° with the 4-fluoro­phenyl, pyridine and phenyl rings, respectively. The 4-fluoro­phenyl ring makes dihedral angles of 77.91 (7) and 26.93 (8)° with the pyridine and phenyl rings, respectively. The phenyl and pyridine rings are nearly perpendicular, making a dihedral angle of 86.47 (9)°. The crystal packing shows an inter­molecular N—H⋯O hydrogen-bonding inter­action between the N—H and carbonyl groups of the amide functions. International Union of Crystallography 2009-11-21 /pmc/articles/PMC2972069/ /pubmed/21578851 http://dx.doi.org/10.1107/S1600536809048661 Text en © Ziegler et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Ziegler, Katharina
Schollmeyer, Dieter
Laufer, Stefan
N-{4-[4-(4-Fluoro­phen­yl)-1-(2-methoxy­ethyl)-2-methyl­sulfanyl-1H-imidazol-5-yl]-2-pyrid­yl}-2-methyl-3-phenyl­propionamide
title N-{4-[4-(4-Fluoro­phen­yl)-1-(2-methoxy­ethyl)-2-methyl­sulfanyl-1H-imidazol-5-yl]-2-pyrid­yl}-2-methyl-3-phenyl­propionamide
title_full N-{4-[4-(4-Fluoro­phen­yl)-1-(2-methoxy­ethyl)-2-methyl­sulfanyl-1H-imidazol-5-yl]-2-pyrid­yl}-2-methyl-3-phenyl­propionamide
title_fullStr N-{4-[4-(4-Fluoro­phen­yl)-1-(2-methoxy­ethyl)-2-methyl­sulfanyl-1H-imidazol-5-yl]-2-pyrid­yl}-2-methyl-3-phenyl­propionamide
title_full_unstemmed N-{4-[4-(4-Fluoro­phen­yl)-1-(2-methoxy­ethyl)-2-methyl­sulfanyl-1H-imidazol-5-yl]-2-pyrid­yl}-2-methyl-3-phenyl­propionamide
title_short N-{4-[4-(4-Fluoro­phen­yl)-1-(2-methoxy­ethyl)-2-methyl­sulfanyl-1H-imidazol-5-yl]-2-pyrid­yl}-2-methyl-3-phenyl­propionamide
title_sort n-{4-[4-(4-fluoro­phen­yl)-1-(2-methoxy­ethyl)-2-methyl­sulfanyl-1h-imidazol-5-yl]-2-pyrid­yl}-2-methyl-3-phenyl­propionamide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972069/
https://www.ncbi.nlm.nih.gov/pubmed/21578851
http://dx.doi.org/10.1107/S1600536809048661
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AT schollmeyerdieter n444fluorophenyl12methoxyethyl2methylsulfanyl1himidazol5yl2pyridyl2methyl3phenylpropionamide
AT lauferstefan n444fluorophenyl12methoxyethyl2methylsulfanyl1himidazol5yl2pyridyl2methyl3phenylpropionamide

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