Methyl­ergometrine maleate from synchrotron powder diffraction data

The title compound {systematic name: 9,10-didehydro-N-[1-(hydroxy­meth­yl)prop­yl]-d-lysergamide maleate}, C(20)H(26)N(3)O(2) (+)·C(4)H(3)O(4) (−), contains a large rigid ergolene group. This group consists of an indole plane connected to a six-membered carbon ring adopting an envelope conformation...

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Autores principales: Rohlíček, Jan, Hušák, Michal, Kratochvíl, Bohumil, Jegorov, Alexandr
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972137/
https://www.ncbi.nlm.nih.gov/pubmed/21578950
http://dx.doi.org/10.1107/S1600536809050351
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author Rohlíček, Jan
Hušák, Michal
Kratochvíl, Bohumil
Jegorov, Alexandr
author_facet Rohlíček, Jan
Hušák, Michal
Kratochvíl, Bohumil
Jegorov, Alexandr
author_sort Rohlíček, Jan
collection PubMed
description The title compound {systematic name: 9,10-didehydro-N-[1-(hydroxy­meth­yl)prop­yl]-d-lysergamide maleate}, C(20)H(26)N(3)O(2) (+)·C(4)H(3)O(4) (−), contains a large rigid ergolene group. This group consists of an indole plane connected to a six-membered carbon ring adopting an envelope conformation and N-methyl­tetra­hydro­pyridine where the methyl group is in an equatorial position. In the crystal, inter­molecular N—H⋯O, O—H⋯N and O—H⋯O hydrogen bonds form an extensive three-dimensional hydrogen-bonding network, which holds the cations and anions together.
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spelling pubmed-29721372010-12-30 Methyl­ergometrine maleate from synchrotron powder diffraction data Rohlíček, Jan Hušák, Michal Kratochvíl, Bohumil Jegorov, Alexandr Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound {systematic name: 9,10-didehydro-N-[1-(hydroxy­meth­yl)prop­yl]-d-lysergamide maleate}, C(20)H(26)N(3)O(2) (+)·C(4)H(3)O(4) (−), contains a large rigid ergolene group. This group consists of an indole plane connected to a six-membered carbon ring adopting an envelope conformation and N-methyl­tetra­hydro­pyridine where the methyl group is in an equatorial position. In the crystal, inter­molecular N—H⋯O, O—H⋯N and O—H⋯O hydrogen bonds form an extensive three-dimensional hydrogen-bonding network, which holds the cations and anions together. International Union of Crystallography 2009-11-28 /pmc/articles/PMC2972137/ /pubmed/21578950 http://dx.doi.org/10.1107/S1600536809050351 Text en © Rohlíček et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Rohlíček, Jan
Hušák, Michal
Kratochvíl, Bohumil
Jegorov, Alexandr
Methyl­ergometrine maleate from synchrotron powder diffraction data
title Methyl­ergometrine maleate from synchrotron powder diffraction data
title_full Methyl­ergometrine maleate from synchrotron powder diffraction data
title_fullStr Methyl­ergometrine maleate from synchrotron powder diffraction data
title_full_unstemmed Methyl­ergometrine maleate from synchrotron powder diffraction data
title_short Methyl­ergometrine maleate from synchrotron powder diffraction data
title_sort methyl­ergometrine maleate from synchrotron powder diffraction data
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972137/
https://www.ncbi.nlm.nih.gov/pubmed/21578950
http://dx.doi.org/10.1107/S1600536809050351
work_keys_str_mv AT rohlicekjan methylergometrinemaleatefromsynchrotronpowderdiffractiondata
AT husakmichal methylergometrinemaleatefromsynchrotronpowderdiffractiondata
AT kratochvilbohumil methylergometrinemaleatefromsynchrotronpowderdiffractiondata
AT jegorovalexandr methylergometrinemaleatefromsynchrotronpowderdiffractiondata

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