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Mice Lacking Alkbh1 Display Sex-Ratio Distortion and Unilateral Eye Defects
BACKGROUND: Eschericia coli AlkB is a 2-oxoglutarate- and iron-dependent dioxygenase that reverses alkylated DNA damage by oxidative demethylation. Mouse AlkB homolog 1 (Alkbh1) is one of eight members of the newly discovered family of mammalian dioxygenases. METHODS AND FINDINGS: In the present stu...
Autores principales: | Nordstrand, Line M., Svärd, Jessica, Larsen, Elisabeth, Nilsen, Anja, Ougland, Rune, Furu, Kari, Lien, Guro F., Rognes, Torbjørn, Namekawa, Satoshi H., Lee, Jeannie T., Klungland, Arne |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972218/ https://www.ncbi.nlm.nih.gov/pubmed/21072209 http://dx.doi.org/10.1371/journal.pone.0013827 |
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