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Intranasal vaccination with messenger RNA as a new approach in gene therapy: Use against tuberculosis
BACKGROUND: mRNAs are highly versatile, non-toxic molecules that are easy to produce and store, which can allow transient protein expression in all cell types. The safety aspects of mRNA-based treatments in gene therapy make this molecule one of the most promising active components of therapeutic or...
Autores principales: | Lorenzi, Julio CC, Trombone, Ana PF, Rocha, Carolina D, Almeida, Luciana P, Lousada, Ricardo L, Malardo, Thiago, Fontoura, Isabela C, Rossetti, Renata AM, Gembre, Ana F, Silva, Aristóbolo M, Silva, Celio L, Coelho-Castelo, Arlete AM |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972232/ https://www.ncbi.nlm.nih.gov/pubmed/20961459 http://dx.doi.org/10.1186/1472-6750-10-77 |
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