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DMF inhibits PDGF-BB induced airway smooth muscle cell proliferation through induction of heme-oxygenase-1

BACKGROUND: Airway wall remodelling is an important pathology of asthma. Growth factor induced airway smooth muscle cell (ASMC) proliferation is thought to be the major cause of airway wall thickening in asthma. Earlier we reported that Dimethylfumarate (DMF) inhibits platelet-derived growth factor...

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Detalles Bibliográficos
Autores principales:	Seidel, Petra, Goulet, Stephanie, Hostettler, Katrin, Tamm, Michael, Roth, Michael
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972257/ https://www.ncbi.nlm.nih.gov/pubmed/20961405 http://dx.doi.org/10.1186/1465-9921-11-145

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