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Relating the shape of protein binding sites to binding affinity profiles: is there an association?

BACKGROUND: Various pattern-based methods exist that use in vitro or in silico affinity profiles for classification and functional examination of proteins. Nevertheless, the connection between the protein affinity profiles and the structural characteristics of the binding sites is still unclear. Our...

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Detalles Bibliográficos
Autores principales: Simon, Zoltán, Vigh-Smeller, Margit, Peragovics, Ágnes, Csukly, Gábor, Zahoránszky-Kőhalmi, Gergely, Rauscher, Anna Á, Jelinek, Balázs, Hári, Péter, Bitter, István, Málnási-Csizmadia, András, Czobor, Pál
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972294/
https://www.ncbi.nlm.nih.gov/pubmed/20923553
http://dx.doi.org/10.1186/1472-6807-10-32