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SEIZURE DURATION AND RELATED ISSUES IN ECT FOR ENDOGENOUS DEPRESSION

In a study comparing sinusoidal wave and brief-pulse ECT in endogenous depression, seizure duration was monitored by the cuff method in 29 patients over 180 treatment sessions. Mean seizure duration across all treatments was 26.5 secs, and the mean for individual patients across their ECT course ran...

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Autor principal: Andrade, Chittaranjan
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972568/
https://www.ncbi.nlm.nih.gov/pubmed/21776168
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author Andrade, Chittaranjan
author_facet Andrade, Chittaranjan
author_sort Andrade, Chittaranjan
collection PubMed
description In a study comparing sinusoidal wave and brief-pulse ECT in endogenous depression, seizure duration was monitored by the cuff method in 29 patients over 180 treatment sessions. Mean seizure duration across all treatments was 26.5 secs, and the mean for individual patients across their ECT course ranged from a minimum of 15.7 secs to maximum of38.5 secs. Regression analysis found no variable which significantly predicted mean seizure duration. Of the 22 good responders in the study, response to ECT was associated with a mean seizure duration of secs in 1 patient, ando cs in 11 patients; as just 2 of 7poor responders to ECT had a mean seizure duration of <20 secs in 1 patients, <25 secs in 11 patients, of the 22 good responders in the study; as just 2 of 7 poor responders to ECT had a mean seizure duration of <25 secs, it appears that a cuff seizure duration of over 20 secs may suffice for the seizure to be therapeutic in depression. With (constant current) brief pulse ECT, seizure threshold significantly increased with successive ECTs; thresholds did not however differ between the good and poor responders. There was a trend for seizure duration to decrease over time; again, good and poor responders did not differ. These findings provide little support for the anticonvulsant hypothesis for the antidepressant effect of ECT, but support the literature that ECT exerts an anticonvulsant effect.
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spelling pubmed-29725682011-07-20 SEIZURE DURATION AND RELATED ISSUES IN ECT FOR ENDOGENOUS DEPRESSION Andrade, Chittaranjan Indian J Psychiatry Original Article In a study comparing sinusoidal wave and brief-pulse ECT in endogenous depression, seizure duration was monitored by the cuff method in 29 patients over 180 treatment sessions. Mean seizure duration across all treatments was 26.5 secs, and the mean for individual patients across their ECT course ranged from a minimum of 15.7 secs to maximum of38.5 secs. Regression analysis found no variable which significantly predicted mean seizure duration. Of the 22 good responders in the study, response to ECT was associated with a mean seizure duration of secs in 1 patient, ando cs in 11 patients; as just 2 of 7poor responders to ECT had a mean seizure duration of <20 secs in 1 patients, <25 secs in 11 patients, of the 22 good responders in the study; as just 2 of 7 poor responders to ECT had a mean seizure duration of <25 secs, it appears that a cuff seizure duration of over 20 secs may suffice for the seizure to be therapeutic in depression. With (constant current) brief pulse ECT, seizure threshold significantly increased with successive ECTs; thresholds did not however differ between the good and poor responders. There was a trend for seizure duration to decrease over time; again, good and poor responders did not differ. These findings provide little support for the anticonvulsant hypothesis for the antidepressant effect of ECT, but support the literature that ECT exerts an anticonvulsant effect. Medknow Publications 1993 /pmc/articles/PMC2972568/ /pubmed/21776168 Text en Copyright: © Indian Journal of Psychiatry http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Andrade, Chittaranjan
SEIZURE DURATION AND RELATED ISSUES IN ECT FOR ENDOGENOUS DEPRESSION
title SEIZURE DURATION AND RELATED ISSUES IN ECT FOR ENDOGENOUS DEPRESSION
title_full SEIZURE DURATION AND RELATED ISSUES IN ECT FOR ENDOGENOUS DEPRESSION
title_fullStr SEIZURE DURATION AND RELATED ISSUES IN ECT FOR ENDOGENOUS DEPRESSION
title_full_unstemmed SEIZURE DURATION AND RELATED ISSUES IN ECT FOR ENDOGENOUS DEPRESSION
title_short SEIZURE DURATION AND RELATED ISSUES IN ECT FOR ENDOGENOUS DEPRESSION
title_sort seizure duration and related issues in ect for endogenous depression
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972568/
https://www.ncbi.nlm.nih.gov/pubmed/21776168
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