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Dental abnormalities and oral health in patients with Hypophosphatemic rickets

INTRODUCTION: Hypophosphatemic rickets represents a group of heritable renal disorders of phosphate characterized by hypophosphatemia, normal or low serum 1,25 (OH)2 vitamin D and calcium levels. Hypophosphatemia is associated to interglobular dentine and an enlarged pulp chambers. AIM: Our goal was...

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Autores principales: Souza, Melissa Almeida, Valente Soares Junior, Luiz Alberto, dos Santos, Marcela Alves, Vaisbich, Maria Helena
Formato: Texto
Lenguaje:English
Publicado: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972601/
https://www.ncbi.nlm.nih.gov/pubmed/21120305
http://dx.doi.org/10.1590/S1807-59322010001000017
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author Souza, Melissa Almeida
Valente Soares Junior, Luiz Alberto
dos Santos, Marcela Alves
Vaisbich, Maria Helena
author_facet Souza, Melissa Almeida
Valente Soares Junior, Luiz Alberto
dos Santos, Marcela Alves
Vaisbich, Maria Helena
author_sort Souza, Melissa Almeida
collection PubMed
description INTRODUCTION: Hypophosphatemic rickets represents a group of heritable renal disorders of phosphate characterized by hypophosphatemia, normal or low serum 1,25 (OH)2 vitamin D and calcium levels. Hypophosphatemia is associated to interglobular dentine and an enlarged pulp chambers. AIM: Our goal was to verify the dental abnormalities and the oral health condition in these patients. MATERIAL AND METHODS: Prospective study of oral conditions in patients with Hypophosphatemic rickets. This report employed a simple method to be easily reproducible: oral clinical exam and radiographic evaluation. RESULTS: Fourteen patients were studied, 5 males, median age of 11years (4 to 26). Occlusion defects (85,7%) and enamel hypoplasia (57,1%) were significant more frequently than dental abscesses (one patient). We observed enlarged pulp chambers in 43% of the patients and hypoplasia and dentin abnormalities in 14,3%. We could not detect a significant correlation between dental abnormalities and delayed treatment (p>0,05). DMFT index for 6 to 12 years patients (n = 12) showed that the oral health is unsatisfactory (mean DMFT =  5). CONCLUSIONS: Patients with Hypophosphatemic Rickets frequently present dental alterations and these are not completely recovered with the treatment, unless dental abscess and they need a periodical oral examination.
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spelling pubmed-29726012010-11-04 Dental abnormalities and oral health in patients with Hypophosphatemic rickets Souza, Melissa Almeida Valente Soares Junior, Luiz Alberto dos Santos, Marcela Alves Vaisbich, Maria Helena Clinics (Sao Paulo) Clinical Science INTRODUCTION: Hypophosphatemic rickets represents a group of heritable renal disorders of phosphate characterized by hypophosphatemia, normal or low serum 1,25 (OH)2 vitamin D and calcium levels. Hypophosphatemia is associated to interglobular dentine and an enlarged pulp chambers. AIM: Our goal was to verify the dental abnormalities and the oral health condition in these patients. MATERIAL AND METHODS: Prospective study of oral conditions in patients with Hypophosphatemic rickets. This report employed a simple method to be easily reproducible: oral clinical exam and radiographic evaluation. RESULTS: Fourteen patients were studied, 5 males, median age of 11years (4 to 26). Occlusion defects (85,7%) and enamel hypoplasia (57,1%) were significant more frequently than dental abscesses (one patient). We observed enlarged pulp chambers in 43% of the patients and hypoplasia and dentin abnormalities in 14,3%. We could not detect a significant correlation between dental abnormalities and delayed treatment (p>0,05). DMFT index for 6 to 12 years patients (n = 12) showed that the oral health is unsatisfactory (mean DMFT =  5). CONCLUSIONS: Patients with Hypophosphatemic Rickets frequently present dental alterations and these are not completely recovered with the treatment, unless dental abscess and they need a periodical oral examination. Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2010-10 /pmc/articles/PMC2972601/ /pubmed/21120305 http://dx.doi.org/10.1590/S1807-59322010001000017 Text en Copyright © 2010 Hospital das Clínicas da FMUSP http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Science
Souza, Melissa Almeida
Valente Soares Junior, Luiz Alberto
dos Santos, Marcela Alves
Vaisbich, Maria Helena
Dental abnormalities and oral health in patients with Hypophosphatemic rickets
title Dental abnormalities and oral health in patients with Hypophosphatemic rickets
title_full Dental abnormalities and oral health in patients with Hypophosphatemic rickets
title_fullStr Dental abnormalities and oral health in patients with Hypophosphatemic rickets
title_full_unstemmed Dental abnormalities and oral health in patients with Hypophosphatemic rickets
title_short Dental abnormalities and oral health in patients with Hypophosphatemic rickets
title_sort dental abnormalities and oral health in patients with hypophosphatemic rickets
topic Clinical Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972601/
https://www.ncbi.nlm.nih.gov/pubmed/21120305
http://dx.doi.org/10.1590/S1807-59322010001000017
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