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Shox2 mediates Tbx5 activity by regulating Bmp4 in the pacemaker region of the developing heart

Heart formation requires a highly balanced network of transcriptional activation of genes. The homeodomain transcription factor, Shox2, is essential for the formation of the sinoatrial valves and for the development of the pacemaking system. The elucidation of molecular mechanisms underlying the dev...

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Detalles Bibliográficos
Autores principales: Puskaric, Sandra, Schmitteckert, Stefanie, Mori, Alessandro D., Glaser, Anne, Schneider, Katja U., Bruneau, Benoit G., Blaschke, Rüdiger J., Steinbeisser, Herbert, Rappold, Gudrun
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972695/
https://www.ncbi.nlm.nih.gov/pubmed/20858598
http://dx.doi.org/10.1093/hmg/ddq393

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