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Human OGA binds substrates in a conserved peptide recognition groove

Modification of cellular proteins with O-GlcNAc (O-linked N-acetylglucosamine) competes with protein phosphorylation and regulates a plethora of cellular processes. O-GlcNAcylation is orchestrated by two opposing enzymes, O-GlcNAc transferase and OGA (O-GlcNAcase or β-N-acetylglucosaminidase), which...

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Detalles Bibliográficos
Autores principales:	Schimpl, Marianne, Schüttelkopf, Alexander W., Borodkin, Vladimir S., van Aalten, Daan M. F.
Formato:	Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2010
Materias:	Accelerated Publication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973230/ https://www.ncbi.nlm.nih.gov/pubmed/20863279 http://dx.doi.org/10.1042/BJ20101338

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