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Interaction with receptor for activated C-kinase 1 (RACK1) sensitizes the phosphodiesterase PDE4D5 towards hydrolysis of cAMP and activation by protein kinase C

We have previously identified the PKC (protein kinase C)-anchoring protein RACK1 (receptor for activated C-kinase 1), as a specific binding partner for the cAMP-specific phosphodiesterase PDE4D5, suggesting a potential site for cross-talk between the PKC and cAMP signalling pathways. In the present...

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Detalles Bibliográficos
Autores principales:	Bird, Rebecca J., Baillie, George S., Yarwood, Stephen J.
Formato:	Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973232/ https://www.ncbi.nlm.nih.gov/pubmed/20819076 http://dx.doi.org/10.1042/BJ20101010

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