Networks of High Mutual Information Define the Structural Proximity of Catalytic Sites: Implications for Catalytic Residue Identification

Identification of catalytic residues (CR) is essential for the characterization of enzyme function. CR are, in general, conserved and located in the functional site of a protein in order to attain their function. However, many non-catalytic residues are highly conserved and not all CR are conserved...

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Detalles Bibliográficos
Autores principales: Marino Buslje, Cristina, Teppa, Elin, Di Doménico, Tomas, Delfino, José María, Nielsen, Morten
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973806/
https://www.ncbi.nlm.nih.gov/pubmed/21079665
http://dx.doi.org/10.1371/journal.pcbi.1000978

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