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Human Cytomegalovirus Induces TGF-β1 Activation in Renal Tubular Epithelial Cells after Epithelial-to-Mesenchymal Transition

Human cytomegalovirus (HCMV) infection is associated epidemiologically with poor outcome of renal allografts due to mechanisms which remain largely undefined. Transforming growth factor-β1 (TGF-β1), a potent fibrogenic cytokine, is more abundant in rejecting renal allografts that are infected with e...

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Detalles Bibliográficos
Autores principales: Shimamura, Masako, Murphy-Ullrich, Joanne E., Britt, William J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973835/
https://www.ncbi.nlm.nih.gov/pubmed/21079788
http://dx.doi.org/10.1371/journal.ppat.1001170