What differences are detected by superiority trials or ruled out by noninferiority trials? A cross-sectional study on a random sample of two-hundred two-arms parallel group randomized clinical trials

BACKGROUND: The smallest difference to be detected in superiority trials or the largest difference to be ruled out in noninferiority trials is a key determinant of sample size, but little guidance exists to help researchers in their choice. The objectives were to examine the distribution of differen...

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Detalles Bibliográficos
Autores principales: Gayet-Ageron, Angèle, Agoritsas, Thomas, Combescure, Christophe, Bagamery, Krisztina, Courvoisier, Delphine S, Perneger, Thomas V
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973934/
https://www.ncbi.nlm.nih.gov/pubmed/20950464
http://dx.doi.org/10.1186/1471-2288-10-93

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973934/
https://www.ncbi.nlm.nih.gov/pubmed/20950464
http://dx.doi.org/10.1186/1471-2288-10-93

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