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In Vitro HIV-1 Selective Integration into the Target Sequence and Decoy-Effect of the Modified Sequence

Although there have been a few reports that the HIV-1 genome can be selectively integrated into the genomic DNA of cultured host cell, the biochemistry of integration selectivity has not been fully understood. We modified the in vitro integration reaction protocol and developed a reaction system wit...

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Detalles Bibliográficos
Autores principales: Tsuruyama, Tatsuaki, Nakai, Tonau, Hiratsuka, Takuya, Jin, Guang, Nakamura, Takuro, Yoshikawa, Kenichi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973958/
https://www.ncbi.nlm.nih.gov/pubmed/21079805
http://dx.doi.org/10.1371/journal.pone.0013841