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In Vitro HIV-1 Selective Integration into the Target Sequence and Decoy-Effect of the Modified Sequence
Although there have been a few reports that the HIV-1 genome can be selectively integrated into the genomic DNA of cultured host cell, the biochemistry of integration selectivity has not been fully understood. We modified the in vitro integration reaction protocol and developed a reaction system wit...
Autores principales: | Tsuruyama, Tatsuaki, Nakai, Tonau, Hiratsuka, Takuya, Jin, Guang, Nakamura, Takuro, Yoshikawa, Kenichi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973958/ https://www.ncbi.nlm.nih.gov/pubmed/21079805 http://dx.doi.org/10.1371/journal.pone.0013841 |
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