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The protein kinase Pak4 disrupts mammary acinar architecture and promotes mammary tumorigenesis
The Pak4 serine/threonine kinase is highly expressed in many cancer cell lines and human tumors. While several studies have addressed the role for Pak4 in transformation of fibroblasts, most human cancers are epithelial in origin. Epithelial cancers are associated not only with changes in cell growt...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974003/ https://www.ncbi.nlm.nih.gov/pubmed/20697354 http://dx.doi.org/10.1038/onc.2010.329 |