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Ultrasound-Enhanced Drug Transport and Distribution in the Brain
Drug delivery in the brain is limited by slow drug diffusion in the brain tissue. This study tested the hypothesis that ultrasound can safely enhance the permeation of drugs in the brain. In vitro exposure to ultrasound at various frequencies (85 kHz, 174 kHz, and 1 MHz) enhanced the permeation of t...
Autores principales: | Liu, Ying, Paliwal, Sumit, Bankiewicz, Krystof S., Bringas, John R., Heart, Gill, Mitragotri, Samir, Prausnitz, Mark R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer US
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974134/ https://www.ncbi.nlm.nih.gov/pubmed/20532711 http://dx.doi.org/10.1208/s12249-010-9458-0 |
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