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Selective killing of human immunodeficiency virus infected cells by non-nucleoside reverse transcriptase inhibitor-induced activation of HIV protease

BACKGROUND: Current antiretroviral therapy against human immunodeficiency virus (HIV-1) reduces viral load and thereby prevents viral spread, but it cannot eradicate proviral genomes from infected cells. Cells in immunological sanctuaries as well as cells producing low levels of virus apparently con...

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Detalles Bibliográficos
Autores principales: Jochmans, Dirk, Anders, Maria, Keuleers, Inge, Smeulders, Liesbeth, Kräusslich, Hans-Georg, Kraus, Günter, Müller, Barbara
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974656/
https://www.ncbi.nlm.nih.gov/pubmed/20950436
http://dx.doi.org/10.1186/1742-4690-7-89