Analysis of binding properties and specificity through identification of the interface forming residues (IFR) for serine proteases in silico docked to different inhibitors

BACKGROUND: Enzymes belonging to the same super family of proteins in general operate on variety of substrates and are inhibited by wide selection of inhibitors. In this work our main objective was to expand the scope of studies that consider only the catalytic and binding pocket amino acids while a...

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Detalles Bibliográficos
Autores principales: Ribeiro, Cristina, Togawa, Roberto C, Neshich, Izabella AP, Mazoni, Ivan, Mancini, Adauto L, Minardi, Raquel C de Melo, da Silveira, Carlos H, Jardine, José G, Santoro, Marcelo M, Neshich, Goran
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974730/
https://www.ncbi.nlm.nih.gov/pubmed/20961427
http://dx.doi.org/10.1186/1472-6807-10-36

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