Biomarker Testing to Estimate Under-Reported Heavy Alcohol Consumption by Persons with HIV Initiating ART in Uganda

Alcohol affects the transmission and treatment of HIV, yet may be under-reported in resource-limited settings. We compared self-reported alcohol consumption with levels of plasma carbohydrate-deficient transferrin (%CDT), a biomarker of heavy alcohol consumption, in persons initiating antiretroviral...

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Detalles Bibliográficos
Autores principales: Hahn, Judith A., Bwana, Mwebesa B., Javors, Martin A., Martin, Jeffrey N., Emenyonu, Nneka I., Bangsberg, David R.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974914/
https://www.ncbi.nlm.nih.gov/pubmed/20697796
http://dx.doi.org/10.1007/s10461-010-9768-y
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author Hahn, Judith A.
Bwana, Mwebesa B.
Javors, Martin A.
Martin, Jeffrey N.
Emenyonu, Nneka I.
Bangsberg, David R.
author_facet Hahn, Judith A.
Bwana, Mwebesa B.
Javors, Martin A.
Martin, Jeffrey N.
Emenyonu, Nneka I.
Bangsberg, David R.
author_sort Hahn, Judith A.
collection PubMed
description Alcohol affects the transmission and treatment of HIV, yet may be under-reported in resource-limited settings. We compared self-reported alcohol consumption with levels of plasma carbohydrate-deficient transferrin (%CDT), a biomarker of heavy alcohol consumption, in persons initiating antiretroviral therapy in Uganda. Almost seven percent (6.7%) of persons reporting abstaining and 10% reporting consuming 1–40 drinks in the prior month tested positive for %CDT, and actual under-report may be higher due to low sensitivity of %CDT. These results suggest likely under-report in those reporting abstaining and current drinking. Improved identification of heavy alcohol consumption is needed for research and clinical purposes.
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spelling pubmed-29749142010-11-29 Biomarker Testing to Estimate Under-Reported Heavy Alcohol Consumption by Persons with HIV Initiating ART in Uganda Hahn, Judith A. Bwana, Mwebesa B. Javors, Martin A. Martin, Jeffrey N. Emenyonu, Nneka I. Bangsberg, David R. AIDS Behav Brief Report Alcohol affects the transmission and treatment of HIV, yet may be under-reported in resource-limited settings. We compared self-reported alcohol consumption with levels of plasma carbohydrate-deficient transferrin (%CDT), a biomarker of heavy alcohol consumption, in persons initiating antiretroviral therapy in Uganda. Almost seven percent (6.7%) of persons reporting abstaining and 10% reporting consuming 1–40 drinks in the prior month tested positive for %CDT, and actual under-report may be higher due to low sensitivity of %CDT. These results suggest likely under-report in those reporting abstaining and current drinking. Improved identification of heavy alcohol consumption is needed for research and clinical purposes. Springer US 2010-08-10 2010 /pmc/articles/PMC2974914/ /pubmed/20697796 http://dx.doi.org/10.1007/s10461-010-9768-y Text en © The Author(s) 2010 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Brief Report
Hahn, Judith A.
Bwana, Mwebesa B.
Javors, Martin A.
Martin, Jeffrey N.
Emenyonu, Nneka I.
Bangsberg, David R.
Biomarker Testing to Estimate Under-Reported Heavy Alcohol Consumption by Persons with HIV Initiating ART in Uganda
title Biomarker Testing to Estimate Under-Reported Heavy Alcohol Consumption by Persons with HIV Initiating ART in Uganda
title_full Biomarker Testing to Estimate Under-Reported Heavy Alcohol Consumption by Persons with HIV Initiating ART in Uganda
title_fullStr Biomarker Testing to Estimate Under-Reported Heavy Alcohol Consumption by Persons with HIV Initiating ART in Uganda
title_full_unstemmed Biomarker Testing to Estimate Under-Reported Heavy Alcohol Consumption by Persons with HIV Initiating ART in Uganda
title_short Biomarker Testing to Estimate Under-Reported Heavy Alcohol Consumption by Persons with HIV Initiating ART in Uganda
title_sort biomarker testing to estimate under-reported heavy alcohol consumption by persons with hiv initiating art in uganda
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974914/
https://www.ncbi.nlm.nih.gov/pubmed/20697796
http://dx.doi.org/10.1007/s10461-010-9768-y
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