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The Role of HDAC6 in Cancer
Histone deacetylase 6 (HDAC6), a member of the HDAC family whose major substrate is α-tubulin, has become a target for drug development to treat cancer due to its major contribution in oncogenic cell transformation. Overexpression of HDAC6 correlates with tumorigenesis and improved survival; therefo...
Autores principales: | Aldana-Masangkay, Grace I., Sakamoto, Kathleen M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975074/ https://www.ncbi.nlm.nih.gov/pubmed/21076528 http://dx.doi.org/10.1155/2011/875824 |
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