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Specific roles for DEG/ENaC and TRP channels in touch and thermosensation in C. elegans nociceptors

Polymodal nociceptors detect noxious stimuli including harsh touch, toxic chemicals, and extremes of heat and cold. The molecular mechanisms by which nociceptors are able to sense multiple qualitatively distinct stimuli are not well-understood. We show here that the C. elegans PVD neurons are muliti...

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Detalles Bibliográficos
Autores principales: Chatzigeorgiou, Marios, Yoo, Sungjae, Watson, Joseph D., Lee, Wei-Hsiang, Spencer, W. Clay, Kindt, Katie S., Hwang, Sun Wook, Miller, David M., Treinin, Millet, Driscoll, Monica, Schafer, William R.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975101/
https://www.ncbi.nlm.nih.gov/pubmed/20512132
http://dx.doi.org/10.1038/nn.2581