Cargando…
Sequence feature-based prediction of protein stability changes upon amino acid substitutions
BACKGROUND: Protein destabilization is a common mechanism by which amino acid substitutions cause human diseases. Although several machine learning methods have been reported for predicting protein stability changes upon amino acid substitutions, the previous studies did not utilize relevant sequenc...
| Autores principales: | , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975416/ https://www.ncbi.nlm.nih.gov/pubmed/21047386 http://dx.doi.org/10.1186/1471-2164-11-S2-S5 |