The Structural Complexity of the Human BORIS Gene in Gametogenesis and Cancer

BACKGROUND: BORIS/CTCFL is a paralogue of CTCF, the major epigenetic regulator of vertebrate genomes. BORIS is normally expressed only in germ cells but is aberrantly activated in numerous cancers. While recent studies demonstrated that BORIS is a transcriptional activator of testis-specific genes,...

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Detalles Bibliográficos
Autores principales: Pugacheva, Elena M., Suzuki, Teruhiko, Pack, Svetlana D., Kosaka-Suzuki, Natsuki, Yoon, Jeongheon, Vostrov, Alexander A., Barsov, Eugene, Strunnikov, Alexander V., Morse, Herbert C., Loukinov, Dmitri, Lobanenkov, Victor
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975627/
https://www.ncbi.nlm.nih.gov/pubmed/21079786
http://dx.doi.org/10.1371/journal.pone.0013872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975627/
https://www.ncbi.nlm.nih.gov/pubmed/21079786
http://dx.doi.org/10.1371/journal.pone.0013872

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