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A Novel Target of Action of Minocycline in NGF-Induced Neurite Outgrowth in PC12 Cells: Translation Initiation Factor eIF4AI

BACKGROUND: Minocycline, a second-generation tetracycline antibiotic, has potential activity for the treatment of several neurodegenerative and psychiatric disorders. However, its mechanisms of action remain to be determined. METHODOLOGY/PRINCIPAL FINDINGS: We found that minocycline, but not tetracy...

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Detalles Bibliográficos
Autores principales: Hashimoto, Kenji, Ishima, Tamaki
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975708/
https://www.ncbi.nlm.nih.gov/pubmed/21151481
http://dx.doi.org/10.1371/journal.pone.0015430

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