C. elegans Mutant Identification with a One-Step Whole-Genome-Sequencing and SNP Mapping Strategy

Whole-genome sequencing (WGS) is becoming a fast and cost-effective method to pinpoint molecular lesions in mutagenized genetic model systems, such as Caenorhabditis elegans. As mutagenized strains contain a significant mutational load, it is often still necessary to map mutations to a chromosomal i...

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Detalles Bibliográficos
Autores principales: Doitsidou, Maria, Poole, Richard J., Sarin, Sumeet, Bigelow, Henry, Hobert, Oliver
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975709/
https://www.ncbi.nlm.nih.gov/pubmed/21079745
http://dx.doi.org/10.1371/journal.pone.0015435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975709/
https://www.ncbi.nlm.nih.gov/pubmed/21079745
http://dx.doi.org/10.1371/journal.pone.0015435

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