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C. elegans Mutant Identification with a One-Step Whole-Genome-Sequencing and SNP Mapping Strategy
Whole-genome sequencing (WGS) is becoming a fast and cost-effective method to pinpoint molecular lesions in mutagenized genetic model systems, such as Caenorhabditis elegans. As mutagenized strains contain a significant mutational load, it is often still necessary to map mutations to a chromosomal i...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975709/ https://www.ncbi.nlm.nih.gov/pubmed/21079745 http://dx.doi.org/10.1371/journal.pone.0015435 |