The Friedreich's ataxia protein frataxin modulates DNA base excision repair in prokaryotes and mammals

DNA-repair mechanisms enable cells to maintain their genetic information by protecting it from mutations that may cause malignant growth. Recent evidence suggests that specific DNA-repair enzymes contain ISCs (iron–sulfur clusters). The nuclearencoded protein frataxin is essential for the mitochondr...

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Detalles Bibliográficos
Autores principales: Thierbach, René, Drewes, Gunnar, Fusser, Markus, Voigt, Anja, Kuhlow, Doreen, Blume, Urte, Schulz, Tim J., Reiche, Carina, Glatt, Hansruedi, Epe, Bernd, Steinberg, Pablo, Ristow, Michael
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976068/
https://www.ncbi.nlm.nih.gov/pubmed/20819074
http://dx.doi.org/10.1042/BJ20101116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976068/
https://www.ncbi.nlm.nih.gov/pubmed/20819074
http://dx.doi.org/10.1042/BJ20101116

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