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Synthesis and Immunological Characterization of Toll-Like Receptor 7 Agonistic Conjugates

Activation of toll-like receptors (TLRs) on cells of the innate immune system initiates, amplifies, and directs the antigen-specific acquired immune response. Ligands that stimulate TLRs, therefore, represent potential immune adjuvants. In this study, a potent TLR7 agonist was conjugated to phosphol...

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Detalles Bibliográficos
Autores principales:	Chan, Michael, Hayashi, Tomoko, Kuy, Crystal S., Gray, Christine S., Wu, Christina C. N., Corr, Maripat, Wrasidlo, Wolfgang, Cottam, Howard B., Carson, Dennis A.
Formato:	Texto
Lenguaje:	English
Publicado:	American Chemical Society 2009
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976567/ https://www.ncbi.nlm.nih.gov/pubmed/19445505 http://dx.doi.org/10.1021/bc900054q

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